一种古老植物散沫花（指甲花）：对皮肤癣菌的体外抗真菌活性测定

An ancient plant Lawsonia inermis (henna): determination of in vitro antifungal activity against dermatophytes species.

作者信息

Gozubuyuk G S, Aktas E, Yigit N

机构信息

Microbiology and Clinical Microbiology Department, Ataturk University Medical Faculties, Erzurum, Turkey.

Medical Laboratory Department, Ataturk University Health Services Vocational Training School, 25070 Erzurum, Turkey.

出版信息

J Mycol Med. 2014 Dec;24(4):313-8. doi: 10.1016/j.mycmed.2014.07.002. Epub 2014 Oct 17.

DOI:10.1016/j.mycmed.2014.07.002

PMID:25442917

Abstract

World is endowed with a rich wealth of medicinal plants. There is a widespread belief that green medicines are healthier and more harmless or safer than synthetic ones. Medicinal plants have been used to cure a number of diseases. The ancient plant Lawsonia inermis or henna is used as medicinal plant because of its attributed strong fungicidal, anti-inflammatory, analgesic, antibacterial, virucidal, antiparasitic, antiamoebiasis, astringent, antihemorrhagic, hypotensive, sedative, anticancer effect and possible anti-sweating properties. In this study, we investigated antifungal activity of L. inermis against clinical dermatophytes species. This study was carried out using 70 clinical isolates of dermatophytes representing six different species; 44 Trichophyton rubrum, 8 Trichophyton mentagrophytes, 6 Microsporum canis, 6 Trichophyton tonsurans, 4 Epidermophyton floccosum, and 2 Trichophyton violaceum. The antifungal activity of L. inermis (henna) was determined by agar diffusion method and henna was used as paste form. Henna paste showed the high antifungal activity against all dermatophytes species (20 to 50mm inhibition zone).

摘要

世界拥有丰富的药用植物资源。人们普遍认为天然药物比合成药物更健康、危害更小或更安全。药用植物已被用于治疗多种疾病。古老的植物散沫花（Lawsonia inermis）或指甲花因其具有强大的杀真菌、抗炎、止痛、抗菌、杀病毒、抗寄生虫、抗阿米巴病、收敛、抗出血、降血压、镇静、抗癌作用以及可能的止汗特性而被用作药用植物。在本研究中，我们调查了散沫花对临床皮肤癣菌的抗真菌活性。本研究使用了代表六种不同物种的70株皮肤癣菌临床分离株进行；44株红色毛癣菌、8株须癣毛癣菌、6株犬小孢子菌、6株断发毛癣菌、4株絮状表皮癣菌和2株紫色毛癣菌。通过琼脂扩散法测定散沫花（指甲花）的抗真菌活性，散沫花以糊状形式使用。指甲花糊对所有皮肤癣菌物种均表现出高抗真菌活性（抑菌圈为20至50毫米）。