绒毛膜羊膜炎的当前管理及长期预后
Current management and long-term outcomes following chorioamnionitis.
作者信息
Johnson Clark T, Farzin Azadeh, Burd Irina
机构信息
Department of Gynecology and Obstetrics, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Phipps 228, Baltimore, MD 21287, USA; Integrated Research Center for Fetal Medicine, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Phipps 217, Baltimore, MD 21287, USA.
Integrated Research Center for Fetal Medicine, Johns Hopkins Medical Institutions, 600 North Wolfe Street, Phipps 217, Baltimore, MD 21287, USA; Department of Pediatrics, Johns Hopkins Medical Institutions, 1800 Orleans Street, Baltimore, MD 21287, USA; International Center for Maternal & Newborn Health, Johns Hopkins University, 605 North Wolfe Street, Baltimore, MD 21287, USA.
出版信息
Obstet Gynecol Clin North Am. 2014 Dec;41(4):649-69. doi: 10.1016/j.ogc.2014.08.007. Epub 2014 Nov 20.
Chorioamnionitis is the process of active infection within the amniotic cavity that induces an inflammatory response. A wide variety of pathologic organisms can cause chorioamnionitis. Prompt diagnosis and timely treatment with broad-spectrum antibiotics can help avert the significant short-term and long-term consequences that may result. This review aims to summarize the up-to-date diagnosis criteria, treatment protocols, and long-term sequelae of missed diagnoses or poorly treated disease. It also calls for future studies that aim to better understand the mechanism of disease and to develop better detection and intervention methods to prevent the significant associated morbidity.
绒毛膜羊膜炎是羊膜腔内的主动感染过程，可引发炎症反应。多种致病生物可导致绒毛膜羊膜炎。及时诊断并使用广谱抗生素进行治疗有助于避免可能产生的严重短期和长期后果。本综述旨在总结最新的诊断标准、治疗方案以及漏诊或治疗不当疾病的长期后遗症。它还呼吁开展未来研究，以更好地了解疾病机制，并开发更好的检测和干预方法，以预防相关的严重发病率。
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