Delbrassinne Laurence, Botteldoorn Nadine, Andjelkovic Mirjana, Dierick Katelijne, Denayer Sarah
1 Scientific Service Food-borne Pathogens, National Reference Laboratory for Food-borne Outbreaks, Scientific Institute of Public Health , Brussels, Belgium .
Foodborne Pathog Dis. 2015 Jan;12(1):84-7. doi: 10.1089/fpd.2014.1788. Epub 2014 Dec 2.
A Bacillus cereus-related emetic outbreak was reported in a Belgian kindergarten. High levels of emetic B. cereus (>1.5E+07 colony-forming units/g) were detected in the food leftovers, and the presence of an emetic strain was confirmed in feces. Emetic toxin levels ranging up to 4.2 μg/g were also quantified in the leftovers by liquid chromatography coupled to tandem mass spectrometry (LC-MS(2)) analysis. Those levels, although moderate in comparison with earlier published intoxications, provoked profuse-vomiting episodes in 20 toddlers aged between 10 and 18 months. Few studies have focused on the levels of emetic toxin implicated in food intoxications. This publication emphasizes the importance of defining toxic doses of emetic toxin among high-risk population groups.
比利时一家幼儿园报告了一起与蜡样芽孢杆菌相关的呕吐性疾病暴发事件。在食物残渣中检测到高水平的呕吐性蜡样芽孢杆菌（>1.5E+07 菌落形成单位/克），并在粪便中确认存在呕吐性菌株。通过液相色谱-串联质谱（LC-MS(2)）分析，还对食物残渣中的呕吐毒素水平进行了定量，最高可达4.2μg/g。尽管与早期公布的中毒事件相比，这些水平适中，但仍导致了20名10至18个月大的幼儿出现大量呕吐发作。很少有研究关注与食物中毒相关的呕吐毒素水平。本出版物强调了在高危人群中确定呕吐毒素毒性剂量的重要性。
