Shibata Tatsuya, Nishio Jun, Matsunaga Taiki, Aoki Mikiko, Iwasaki Hiroshi, Naito Masatoshi
Departments of Orthopaedic Surgery and Fukuoka University, Fukuoka 814-0180, Japan.
Departments of Pathology, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan.
Mol Clin Oncol. 2015 Jan;3(1):207-211. doi: 10.3892/mco.2014.433. Epub 2014 Oct 1.
The patella is a rare site for the development of primary tumors. This is the case report of a giant cell tumor (GCT) occurring in the patella in a 25-year-old woman. The patient presented with a 1-year history of occasional right anterior knee pain. The radiological characteristics suggested a benign condition. The intraoperative pathological diagnosis was GCT of the bone. The lesion was treated by radical curettage with adjuvant therapy comprising phenol and ethanol and injection of calcium phosphate cement. Histologically, the tumor consisted of round or spindle-shaped mononuclear cells admixed with numerous osteoclastic giant cells. The patient was asymptomatic and there was no evidence of local recurrence or distant metastasis 16 months after surgery. Although rare, patellar GCT may be included in the differential diagnosis of anterior knee pain and/or swelling, particularly in young adults.
髌骨是原发性肿瘤发生的罕见部位。本文报告了一名25岁女性髌骨发生的骨巨细胞瘤(GCT)病例。患者有1年偶尔右膝前疼痛的病史。放射学特征提示为良性病变。术中病理诊断为骨巨细胞瘤。病变采用根治性刮除术治疗,辅助治疗包括苯酚和乙醇,并注射磷酸钙骨水泥。组织学上,肿瘤由圆形或梭形单核细胞与大量破骨细胞样巨细胞混合组成。患者无症状,术后16个月无局部复发或远处转移的证据。尽管罕见,但髌骨骨巨细胞瘤可能应纳入膝前疼痛和/或肿胀的鉴别诊断,尤其是在年轻人中。