Nikolaou Panayiotis, Goodson Boyd M, Chekmenev Eduard Y
Institute of Imaging Science (VUIIS), Department of Radiology, Department of Biomedical Engineering, Department of Physics and Astronomy and Department of Biochemistry, Vanderbilt-Ingram Cancer Center (VICC), Vanderbilt University, 1161 21st Ave South AA-1107, Nashville, Tennessee, 37232-2310 (USA).
Chemistry. 2015 Feb 16;21(8):3156-66. doi: 10.1002/chem.201405253. Epub 2014 Dec 3.
Recent developments in NMR hyperpolarization have enabled a wide array of new in vivo molecular imaging modalities, ranging from functional imaging of the lungs to metabolic imaging of cancer. This Concept article explores selected advances in methods for the preparation and use of hyperpolarized contrast agents, many of which are already at or near the phase of their clinical validation in patients.
核磁共振超极化技术的最新进展催生了一系列新的体内分子成像模式，从肺部功能成像到癌症代谢成像。这篇概念文章探讨了超极化造影剂制备和使用方法的一些选定进展，其中许多已经处于或接近在患者中进行临床验证的阶段。
