拓展病毒组的作用：肠道中的共生关系
Expanding the role of the virome: commensalism in the gut.
作者信息
Cadwell Ken
机构信息
Kimmel Center for Biology and Medicine at the Skirball Institute, Department of Microbiology, New York University School of Medicine, New York, New York, USA
出版信息
J Virol. 2015 Feb;89(4):1951-3. doi: 10.1128/JVI.02966-14. Epub 2014 Dec 10.
Abstract
Viruses affect host physiology beyond causing acute disease, thereby giving rise to the concept that the virome is a component of the microbiome. However, the role of the enteric virome is understudied relative to the fast-paced research examining commensal bacteria in the intestine. In this article, I discuss our recent work on murine norovirus indicating that an animal virus in the intestine can provide many of the signals to the host that have been attributed to commensal bacteria. Our findings suggest that the surge in microbiome research should incorporate examination of the enteric virome.
摘要
病毒对宿主生理的影响不仅限于引发急性疾病，从而催生了病毒组是微生物组组成部分的概念。然而，相对于对肠道共生细菌的快节奏研究，肠道病毒组的作用尚未得到充分研究。在本文中，我将讨论我们最近关于小鼠诺如病毒的研究工作，该研究表明肠道中的动物病毒可以向宿主提供许多归因于共生细菌的信号。我们的研究结果表明，微生物组研究的热潮应纳入对肠道病毒组的研究。
相似文献
1
Expanding the role of the virome: commensalism in the gut.
J Virol. 2015 Feb;89(4):1951-3. doi: 10.1128/JVI.02966-14. Epub 2014 Dec 10.
2
Gut inflammation and immunity: what is the role of the human gut virome?
Mediators Inflamm. 2015;2015:326032. doi: 10.1155/2015/326032. Epub 2015 Apr 7.
3
The human gut microbiota and virome: Potential therapeutic implications.
Dig Liver Dis. 2015 Dec;47(12):1007-12. doi: 10.1016/j.dld.2015.07.008. Epub 2015 Jul 18.
4
Gut Virome and Inflammatory Bowel Disease.
Inflamm Bowel Dis. 2016 Jul;22(7):1708-12. doi: 10.1097/MIB.0000000000000807.
5
The dark side of the gut: Virome-host interactions in intestinal homeostasis and disease.
J Exp Med. 2021 May 3;218(5). doi: 10.1084/jem.20201044.
6
Enteric viruses evoke broad host immune responses resembling those elicited by the bacterial microbiome.
Cell Host Microbe. 2021 Jun 9;29(6):1014-1029.e8. doi: 10.1016/j.chom.2021.03.015. Epub 2021 Apr 23.
7
Beyond the gut bacterial microbiota: The gut virome.
J Med Virol. 2016 Sep;88(9):1467-72. doi: 10.1002/jmv.24508. Epub 2016 Mar 11.
8
What is (not) known about the dynamics of the human gut virome in health and disease.
Curr Opin Virol. 2019 Aug;37:52-57. doi: 10.1016/j.coviro.2019.05.013. Epub 2019 Jun 27.
9
The role of virome in the gastrointestinal tract and beyond.
FEMS Microbiol Rev. 2022 Nov 2;46(6). doi: 10.1093/femsre/fuac027.
10
The Bacterial Microbiome and Virome Milestones of Infant Development.
Trends Microbiol. 2016 Oct;24(10):801-810. doi: 10.1016/j.tim.2016.06.001. Epub 2016 Jun 25.
引用本文的文献
1
Effects and mechanisms of infection on the occurrence of extra-gastric tumors.
World J Gastroenterol. 2024 Oct 7;30(37):4090-4103. doi: 10.3748/wjg.v30.i37.4090.
2
Activation of Nod2 signaling upon norovirus infection enhances antiviral immunity and susceptibility to colitis.
Gut Microbes. 2023 Dec;15(2):2249960. doi: 10.1080/19490976.2023.2249960.
3
Crosstalk between the Intestinal Virome and Other Components of the Microbiota, and Its Effect on Intestinal Mucosal Response and Diseases.
J Immunol Res. 2022 Sep 27;2022:7883945. doi: 10.1155/2022/7883945. eCollection 2022.
4
Detection of Ancient Viruses and Long-Term Viral Evolution.
Viruses. 2022 Jun 18;14(6):1336. doi: 10.3390/v14061336.
5
The Interplay between the Host Microbiome and Pathogenic Viral Infections.
mBio. 2021 Dec 21;12(6):e0249621. doi: 10.1128/mBio.02496-21. Epub 2021 Nov 2.
6
Characterization of the Eukaryotic Virome of Mice from Different Sources.
Microorganisms. 2021 Sep 30;9(10):2064. doi: 10.3390/microorganisms9102064.
7
Viral Metagenome-Based Precision Surveillance of Pig Population at Large Scale Reveals Viromic Signatures of Sample Types and Influence of Farming Management on Pig Virome.
mSystems. 2021 Jun 29;6(3):e0042021. doi: 10.1128/mSystems.00420-21. Epub 2021 Jun 8.
8
Demography, life-history trade-offs, and the gastrointestinal virome of wild chimpanzees.
Philos Trans R Soc Lond B Biol Sci. 2020 Nov 9;375(1811):20190613. doi: 10.1098/rstb.2019.0613. Epub 2020 Sep 21.
9
An Integrated Multi-Disciplinary Perspectivefor Addressing Challenges of the Human Gut Microbiome.
Metabolites. 2020 Mar 6;10(3):94. doi: 10.3390/metabo10030094.
10
The gut virome in inflammatory bowel disease pathogenesis: From metagenomics to novel therapeutic approaches.
United European Gastroenterol J. 2019 Oct;7(8):999-1007. doi: 10.1177/2050640619876787. Epub 2019 Sep 27.
本文引用的文献
1
Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection.
Science. 2015 Jan 16;347(6219):266-9. doi: 10.1126/science.1258025. Epub 2014 Nov 27.
2
Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity.
Science. 2015 Jan 16;347(6219):269-73. doi: 10.1126/science.1258100. Epub 2014 Nov 27.
3
An enteric virus can replace the beneficial function of commensal bacteria.
Nature. 2014 Dec 4;516(7529):94-8. doi: 10.1038/nature13960. Epub 2014 Nov 19.
4
Enteric bacteria promote human and mouse norovirus infection of B cells.
Science. 2014 Nov 7;346(6210):755-9. doi: 10.1126/science.1257147.
5
Coinfection. Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation.
Science. 2014 Aug 1;345(6196):578-82. doi: 10.1126/science.1256942. Epub 2014 Jul 17.
6
Inflammatory bowel disease as a model for translating the microbiome.
Immunity. 2014 Jun 19;40(6):843-54. doi: 10.1016/j.immuni.2014.05.013.
7
The virome in mammalian physiology and disease.
Cell. 2014 Mar 27;157(1):142-50. doi: 10.1016/j.cell.2014.02.032.
8
Resident viruses and their interactions with the immune system.
Nat Immunol. 2013 Jul;14(7):654-9. doi: 10.1038/ni.2614.
9
Microbial exposure during early life has persistent effects on natural killer T cell function.
Science. 2012 Apr 27;336(6080):489-93. doi: 10.1126/science.1219328. Epub 2012 Mar 22.
10
The microbiome in infectious disease and inflammation.
Annu Rev Immunol. 2012;30:759-95. doi: 10.1146/annurev-immunol-020711-074937. Epub 2012 Jan 6.
Zotero 插件