Laboratory of Parasite and Vector Biology, Institute of Tropical Zoology and Ecology, Science Faculty, Central University of Venezuela , Caracas , Venezuela.
Front Public Health. 2014 Nov 28;2:259. doi: 10.3389/fpubh.2014.00259. eCollection 2014.
Trypanosoma cruzi the etiological agent of American Trypanosomiasis or Chagas disease (ChD) is transmitted by triatomines vectors between mammals including man. T. cruzi has existed for circa 150 Ma in the Americas and nearly 10 million people are currently infected. The overlap between wild and domestic ecotopes where T. cruzi circulates is increasing. Host-parasite interactions have been determined by infection patterns in these cycles, all under natural or laboratorial conditions. This mini-review describes specific parasite niches, such as plant communities or biological corridors between domestic and wild landscapes, in order to help identify risk factors for ChD and define the boundaries between wild and domestic transmission cycles, with an emphasis on research undertaken in Venezuela.
克氏锥虫，即恰加斯病（Chagas 病）的病原体，由锥蝽等媒介在哺乳动物（包括人类）之间传播。克氏锥虫在美洲存在了大约 1.5 亿年，目前约有 1000 万人受到感染。锥虫在野生和家养生态区之间的重叠正在增加。宿主-寄生虫相互作用已通过这些循环中的感染模式确定，所有这些都是在自然或实验室条件下进行的。本综述描述了特定的寄生虫生态位，例如植物群落或在野生和家养景观之间的生物走廊，以帮助确定 Chagas 病的风险因素，并定义野生和家养传播循环之间的界限，重点是在委内瑞拉开展的研究。
