Van Dong Hoang, Lee Andy H, Nga Nguyen Hoai, Quang Nguyen, Le Chuyen Vu, Binns Colin W
Department of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam E-mail :
Asian Pac J Cancer Prev. 2014;15(22):9747-51. doi: 10.7314/apjcp.2014.15.22.9747.
Prostate cancer is the second most common cancer in men worldwide and a leading cause of mortality. Incidences continues to rise and vary substantially between populations. Although the prevalence of prostate cancer is relatively low in Vietnam, some hospital-based reports have shown an upward trend in recent years. While certain non-modifiable factors such as age, race and genetics are known to be mainly responsible, the literature has also suggested that environmental exposures can delay the onset of this disease. The present study provides a review of the epidemiology of prostate cancer in Vietnam by systematically searching several electronic databases. The results confirm an increasing trend of prostate cancer over the past decade, with age-standardised rate more than doubled from 2.2 per 100,000 men in 2000 to 4.7 per 100,000 men in 2010. However, no study has been found on modifiable risk factors, with the exception of one in vitro experiment that showed the inhibitory effect of garlic on the growth of prostate cancer cells. The lack of epidemiological information poses a difficulty to develop public health interventions to prevent this emerging malignant disease in Vietnam.
前列腺癌是全球男性中第二常见的癌症，也是主要的致死原因。其发病率持续上升，且在不同人群之间差异很大。虽然越南前列腺癌的患病率相对较低，但一些基于医院的报告显示近年来呈上升趋势。虽然已知某些不可改变的因素如年龄、种族和基因是主要原因，但文献也表明环境暴露会延迟这种疾病的发病。本研究通过系统检索多个电子数据库，对越南前列腺癌的流行病学进行了综述。结果证实，在过去十年中前列腺癌呈上升趋势，年龄标准化发病率从2000年每10万名男性中的2.2例增加到2010年的每10万名男性中的4.7例，增加了一倍多。然而，除了一项体外实验表明大蒜对前列腺癌细胞生长有抑制作用外，尚未发现关于可改变风险因素的研究。缺乏流行病学信息给制定公共卫生干预措施以预防越南这种新出现的恶性疾病带来了困难。
