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一种来自互隔交链孢菌cib-137的新型互隔交链孢酚糖苷。

A new alternariol glucoside from fungus Alternaria alternate cib-137.

作者信息

Xu Guo-Bo, Pu Xiang, Bai Huan-Huan, Chen Xiao-Zhen, Li Guo-You

机构信息

a Chengdu Institute of Biology, Chinese Academy of Sciences , Chengdu 610041 , P. R. China.

出版信息

Nat Prod Res. 2015;29(9):848-52. doi: 10.1080/14786419.2014.990905. Epub 2014 Dec 18.

Abstract

A new secondary metabolite, 2-O-methylalternariol 4-O-β-[4-methoxyl-glucopyranoside] (1), together with four known compounds alternariol methyl ether (2), altenuene (3), isoaltenuene (4) and 2-(2'S-hydroxypropyl)-5-methyl-7-hydroxychromone (5), was isolated from the fungus Alternaria alternate cib-137. Its structure was elucidated on the basis of spectroscopic data. Compounds 3 and 4 demonstrated moderate activity against Staphylococcus aureus.

摘要

从真菌链格孢菌cib - 137中分离出一种新的次生代谢产物2 - O - 甲基交替链格孢酚4 - O - β - 4 - 甲氧基 - 吡喃葡萄糖苷,以及四种已知化合物交替链格孢酚甲醚(2)、互隔交链孢酚(3)、异互隔交链孢酚(4)和2 - (2' - 羟基丙基)-5 - 甲基 - 7 - 羟基色酮(5)。根据光谱数据阐明了其结构。化合物3和4对金黄色葡萄球菌表现出中等活性。

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