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The application of magnetic nanoparticles for the treatment of brain tumors.

作者信息

Mahmoudi Keon, Hadjipanayis Costas G

机构信息

Georgia Institute of Technology, School of Biology Atlanta, GA, USA.

Brain Tumor Nanotechnology Laboratory, Department of Neurosurgery, Winship Cancer Institute of Emory University, Emory University School of Medicine Atlanta, GA, USA.

出版信息

Front Chem. 2014 Dec 3;2:109. doi: 10.3389/fchem.2014.00109. eCollection 2014.

DOI:10.3389/fchem.2014.00109
PMID:25520952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4253533/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3686/4253533/3f94bc41e3c7/fchem-02-00109-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3686/4253533/3f94bc41e3c7/fchem-02-00109-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3686/4253533/3f94bc41e3c7/fchem-02-00109-g0001.jpg

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Mol Membr Biol. 2014 Aug;31(5):152-67. doi: 10.3109/09687688.2014.937468. Epub 2014 Jul 21.
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A nanoparticle carrying the p53 gene targets tumors including cancer stem cells, sensitizes glioblastoma to chemotherapy and improves survival.携带p53基因的纳米颗粒可靶向包括癌症干细胞在内的肿瘤,使胶质母细胞瘤对化疗敏感并提高生存率。
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Dependence of Brownian and Néel relaxation times on magnetic field strength.
通过各种纳米递药系统提高类胡萝卜素治疗阿尔茨海默病的效果。
Int J Mol Sci. 2023 Apr 21;24(8):7652. doi: 10.3390/ijms24087652.
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Strategies to overcome/penetrate the BBB for systemic nanoparticle delivery to the brain/brain tumor.克服/穿透血脑屏障以实现系统纳米颗粒向脑/脑肿瘤递药的策略。
Adv Drug Deliv Rev. 2022 Dec;191:114619. doi: 10.1016/j.addr.2022.114619. Epub 2022 Nov 11.
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Oxidative stress generated at nickel oxide nanoparticle interface results in bacterial membrane damage leading to cell death.氧化镍纳米颗粒界面产生的氧化应激会导致细菌细胞膜损伤,进而导致细胞死亡。
RSC Adv. 2019 Aug 12;9(43):24888-24894. doi: 10.1039/c9ra02082a. eCollection 2019 Aug 8.
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Crossing the Blood-Brain Barrier: Advances in Nanoparticle Technology for Drug Delivery in Neuro-Oncology.穿越血脑屏障:神经肿瘤学中用于药物递释的纳米颗粒技术的进展。
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