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一生中的饮食、行为与免疫

Diet, behavior and immunity across the lifespan.

作者信息

Hale Matthew W, Spencer Sarah J, Conti Bruno, Jasoni Christine L, Kent Stephen, Radler Morgan E, Reyes Teresa M, Sominsky Luba

机构信息

School of Psychological Science, La Trobe University, Melbourne, VIC, Australia.

School of Health Sciences and Health Innovations Research Institute (HIRi), RMIT University, Melbourne, VIC, Australia.

出版信息

Neurosci Biobehav Rev. 2015 Nov;58:46-62. doi: 10.1016/j.neubiorev.2014.12.009. Epub 2014 Dec 15.

Abstract

It is increasingly appreciated that perinatal events can set an organism on a life-long trajectory for either health or disease, resilience or risk. One early life variable that has proven critical for optimal development is the nutritional environment in which the organism develops. Extensive research has documented the effects of both undernutrition and overnutrition, with strong links evident for an increased risk for obesity and metabolic disorders, as well as adverse mental health outcomes. Recent work has highlighted a critical role of the immune system, in linking diet with long term health and behavioral outcomes. The present review will summarize the recent literature regarding the interactions of diet, immunity, and behavior.

摘要

越来越多的人认识到,围产期事件可以使生物体走上健康或疾病、恢复力或风险的终身轨迹。一个已被证明对最佳发育至关重要的早期生命变量是生物体发育所处的营养环境。广泛的研究记录了营养不足和营养过剩的影响,肥胖、代谢紊乱风险增加以及不良心理健康结果之间存在明显的紧密联系。最近的研究突出了免疫系统在将饮食与长期健康及行为结果联系起来方面的关键作用。本综述将总结关于饮食、免疫和行为相互作用的最新文献。

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