Vanotti Sandra, Cores Evangelina Valeria, Eizaguirre Barbara, Angeles Merino, Rey Raul, Villa Andres, Cáceres Fernando
a Multiple Sclerosis Clinic, Neurosciences Institute of Buenos Aires , Buenos Aires , Argentina.
Appl Neuropsychol Adult. 2015;22(1):46-53. doi: 10.1080/23279095.2013.831866.
The aim of this study was to standardize the Symbol Digit Modalities Test (SDMT)-Oral version in a healthy population living in Argentina and to analyze the influence that age, gender, and education have on the SDMT. Secondarily, it is intended to analyze the performance of patients with multiple sclerosis (MS) on this test. Two hundred ninety-seven healthy participants were evaluated; they had an average age of 39.28 years and 13.87 years of schooling; 77.8% were women. The sample was segmented according to age in three groups: younger than 35 years old, 36 to 50 years old, and 51 to 70 years old. The sample was also segmented according to years of schooling in three groups: 11 years or less, 12 to 16 years, and more than 16 years. All participants were evaluated with the oral version of the SDMT. A clinical sample of 111 patients with MS was also assessed. The mean on the SDMT for the total sample was 51.34 (SD=12.76). The differences were significant between all groups, p<.05, according to age. The participants with a higher level of education performed better than did those with moderate education and those with less schooling, p<.05. There was a significant difference between patients with MS and healthy controls, p<.01. The SDMT is influenced by age as well as by schooling, although not by gender. The norms displayed here will be useful to accurately evaluate the yield of the patients in the neuropsychological clinic when comparing them with their group of reference. It was also demonstrated that the SDMT can discriminate between patients with MS and healthy people.
本研究的目的是在居住于阿根廷的健康人群中对符号数字模式测验（SDMT）的口语版进行标准化，并分析年龄、性别和教育程度对SDMT的影响。其次，旨在分析多发性硬化症（MS）患者在此测试中的表现。对297名健康参与者进行了评估；他们的平均年龄为39.28岁，受教育年限为13.87年；77.8%为女性。样本按年龄分为三组：35岁以下、36至50岁、51至70岁。样本还按受教育年限分为三组：11年及以下、12至16年、16年以上。所有参与者均接受了SDMT口语版的评估。还对111名MS患者的临床样本进行了评估。整个样本在SDMT上的平均分为51.34（标准差=12.76）。根据年龄，所有组之间的差异均具有统计学意义，p<0.05。教育程度较高的参与者比中等教育程度和受教育年限较少的参与者表现更好，p<0.05。MS患者与健康对照组之间存在显著差异，p<0.01。SDMT受年龄和受教育程度的影响，但不受性别的影响。此处展示的常模在将神经心理门诊患者与其参照组进行比较时，将有助于准确评估患者的测试结果。研究还表明，SDMT能够区分MS患者和健康人群。
