Maurizio Pompili, Marco Innamorati, Franco Montebovi, Mariantonietta Milelli, Paolo Girardi, Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy.
World J Psychiatry. 2014 Dec 22;4(4):141-9. doi: 10.5498/wjp.v4.i4.141.
To investigate factors related to hopelessness in a sample of epileptic patients, including measures of depression and quality of life (QOL).
Sixty-nine participants were administered the following psychometric instruments: Beck Depression Inventory-II, Beck Hopelessness Scale (BHS), and QOL in Epilepsy (QOLIE)-89. Patients were dichotomized into two categories: those affected by epilepsy with generalized tonic-clonic seizures vs those having epilepsy with partial seizures.
The groups differed on the QOLIE Role Limitation/Emotional dimension. Patients with generalized seizures reported more limitations in common social/role activities related to emotional problems than patients with other types of epilepsy (89.57 ± 25.49 vs 72.86 ± 36.38; t 63 = -2.16; P < 0.05). All of the respondents reported moderate to severe depression, and 21.7% of patients with generalized seizures and 28.6% of patients with other diagnoses had BHS total scores ≥ 9 indicating a higher suicidal risk. The study did not control for years of the illness.
Patients with generalized seizures reported more limitations in common social/role activities related to emotional problems compared to patients with other types of seizures. Patients at increased suicide risk as evaluated by the BHS were older than those who had a lower suicidal risk. Future studies are required to further investigate the impact of hopelessness on the outcome of epileptic patients.
调查癫痫患者样本中与绝望相关的因素,包括抑郁和生活质量(QOL)的测量。
对 69 名参与者进行了以下心理计量学工具的评估:贝克抑郁量表第二版、贝克绝望量表(BHS)和癫痫生活质量量表(QOLIE)-89。患者被分为两类:全身性强直阵挛性发作的癫痫患者和局灶性发作的癫痫患者。
两组在 QOLIE 角色限制/情绪维度上存在差异。全身性发作的患者在与情绪问题相关的常见社交/角色活动方面报告了更多的限制(89.57±25.49 与 72.86±36.38;t63=-2.16;P<0.05)。所有受访者均报告有中度至重度抑郁,21.7%的全身性发作患者和 28.6%的其他诊断患者的 BHS 总分≥9,表明自杀风险较高。该研究未控制病程年数。
与其他类型的癫痫患者相比,全身性发作的患者在与情绪问题相关的常见社交/角色活动方面报告了更多的限制。根据 BHS 评估,自杀风险较高的患者比自杀风险较低的患者年龄更大。未来的研究需要进一步调查绝望对癫痫患者预后的影响。