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J Affect Disord. 2012 Feb;136(3):405-11. doi: 10.1016/j.jad.2011.11.011. Epub 2011 Dec 16.
3
The economic cost of brain disorders in Europe.欧洲脑部疾病的经济负担。
Eur J Neurol. 2012 Jan;19(1):155-62. doi: 10.1111/j.1468-1331.2011.03590.x.
4
Determinants of health-related quality of life in pharmacoresistant epilepsy: results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments.药物难治性癫痫患者健康相关生活质量的决定因素:一项大型多中心研究的结果,该研究连续纳入了使用经过验证的定量评估方法的患者。
Epilepsia. 2011 Dec;52(12):2181-91. doi: 10.1111/j.1528-1167.2011.03325.x.
5
Quality of life in 1931 adult patients with epilepsy: seizures do not tell the whole story.1931 年成年癫痫患者的生活质量:发作并不能说明全部情况。
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6
Predictors of health-related quality of life and costs in adults with epilepsy: a systematic review.预测成人癫痫患者的健康相关生活质量和成本的因素:系统评价。
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Differential effects of seizure control and affective symptoms on quality of life in people with epilepsy.癫痫患者的癫痫控制和情感症状对生活质量的差异影响。
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Anxiety disorders, subsyndromic depressive episodes, and major depressive episodes: do they differ on their impact on the quality of life of patients with epilepsy?焦虑障碍、亚综合征抑郁发作和重性抑郁发作:它们对癫痫患者生活质量的影响是否不同?
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癫痫患者绝望感的相关因素。

Factors associated with hopelessness in epileptic patients.

机构信息

Maurizio Pompili, Marco Innamorati, Franco Montebovi, Mariantonietta Milelli, Paolo Girardi, Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Center, Sant'Andrea Hospital, Sapienza University of Rome, 00189 Rome, Italy.

出版信息

World J Psychiatry. 2014 Dec 22;4(4):141-9. doi: 10.5498/wjp.v4.i4.141.

DOI:10.5498/wjp.v4.i4.141
PMID:25540729
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4274586/
Abstract

AIM

To investigate factors related to hopelessness in a sample of epileptic patients, including measures of depression and quality of life (QOL).

METHODS

Sixty-nine participants were administered the following psychometric instruments: Beck Depression Inventory-II, Beck Hopelessness Scale (BHS), and QOL in Epilepsy (QOLIE)-89. Patients were dichotomized into two categories: those affected by epilepsy with generalized tonic-clonic seizures vs those having epilepsy with partial seizures.

RESULTS

The groups differed on the QOLIE Role Limitation/Emotional dimension. Patients with generalized seizures reported more limitations in common social/role activities related to emotional problems than patients with other types of epilepsy (89.57 ± 25.49 vs 72.86 ± 36.38; t 63 = -2.16; P < 0.05). All of the respondents reported moderate to severe depression, and 21.7% of patients with generalized seizures and 28.6% of patients with other diagnoses had BHS total scores ≥ 9 indicating a higher suicidal risk. The study did not control for years of the illness.

CONCLUSION

Patients with generalized seizures reported more limitations in common social/role activities related to emotional problems compared to patients with other types of seizures. Patients at increased suicide risk as evaluated by the BHS were older than those who had a lower suicidal risk. Future studies are required to further investigate the impact of hopelessness on the outcome of epileptic patients.

摘要

目的

调查癫痫患者样本中与绝望相关的因素,包括抑郁和生活质量(QOL)的测量。

方法

对 69 名参与者进行了以下心理计量学工具的评估:贝克抑郁量表第二版、贝克绝望量表(BHS)和癫痫生活质量量表(QOLIE)-89。患者被分为两类:全身性强直阵挛性发作的癫痫患者和局灶性发作的癫痫患者。

结果

两组在 QOLIE 角色限制/情绪维度上存在差异。全身性发作的患者在与情绪问题相关的常见社交/角色活动方面报告了更多的限制(89.57±25.49 与 72.86±36.38;t63=-2.16;P<0.05)。所有受访者均报告有中度至重度抑郁,21.7%的全身性发作患者和 28.6%的其他诊断患者的 BHS 总分≥9,表明自杀风险较高。该研究未控制病程年数。

结论

与其他类型的癫痫患者相比,全身性发作的患者在与情绪问题相关的常见社交/角色活动方面报告了更多的限制。根据 BHS 评估,自杀风险较高的患者比自杀风险较低的患者年龄更大。未来的研究需要进一步调查绝望对癫痫患者预后的影响。