Liang Jun, Wang Yu, Dou Lianjun, Li Hongyan, Liu Xuekui, Qiu Qinqin, Qi Lu
aDepartment of Endocrinology, Xuzhou Central Hospital, Xuzhou Clinical School of Xuzhou Medical College, Xuzhou Institute of Medical Sciences, Xuzhou Institute of Diabetes, Affiliated Hospital of Southeast University bXuzhou Medical College, Xuzhou, Jiangsu, China cDepartment of Nutrition, Harvard School of Public Health dChanning Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA *Both Jun Liang and Yu Wang contributed equally to this work.
J Hypertens. 2015 Feb;33(2):275-8. doi: 10.1097/HJH.0000000000000396.
We have previously found that neck circumference was related to insulin resistance, a risk factor for hypertension in Chinese. Little is known about whether high neck circumference is associated with elevated blood pressure.
The study samples were from a community-based health examination survey in central China. In total, 1709 men and women with neck circumference measurement were included. We analysed the associations between neck circumference and the risk of prehypertension.
Although neck circumference was strongly associated with SBP/DBP in a univariate analysis, it was no longer associated with SBP and the association was much weaker with DBP when the association was adjusted for BMI or waist circumference. Similarly, high neck circumference was significantly related to an increased risk of prehypertension [odds ratio 1.254; 95% confidence interval (95% CI) 1.171-1.343] in a univariate analysis, and the association became marginal in models further adjusting for BMI or waist.
Our data suggest that neck circumference as predictor for prehypertension is not obvious given the moderate improvement of disease prediction.
我们之前发现颈围与胰岛素抵抗有关，胰岛素抵抗是中国人患高血压的一个风险因素。关于高颈围是否与血压升高相关，目前知之甚少。
研究样本来自中国中部一项基于社区的健康检查调查。总共纳入了1709名测量了颈围的男性和女性。我们分析了颈围与高血压前期风险之间的关联。
尽管在单变量分析中颈围与收缩压/舒张压密切相关，但在调整体重指数（BMI）或腰围后，它与收缩压不再相关，与舒张压的关联也弱得多。同样，在单变量分析中，高颈围与高血压前期风险增加显著相关[比值比1.254；95%置信区间（95%CI）1.171 - 1.343]，而在进一步调整BMI或腰围的模型中，这种关联变得不显著。
我们的数据表明，鉴于疾病预测的适度改善，颈围作为高血压前期预测指标并不明显。
