From the Department of Vector and Public Health Pest Control, National Center for Epidemiology , Budapest.
Infect Dis (Lond). 2015 Mar;47(3):178-81. doi: 10.3109/00365548.2014.975743. Epub 2014 Dec 31.
Rodents captured in a known tick-borne encephalitis virus (TBEV) focus were serologically surveyed for 4 years, with 28 visits. The collected sera were analysed by virus neutralization test. Bank vole (Myodes glareolus) had a significantly higher incidence rate of antibodies to TBEV (20.5%) than Apodemus flavicollis (3.7%) and Apodemus agrarius (4.6%). In all species, rates were higher in adults (6.8%) than in juveniles (1.7%). A higher incidence rate was observed in female A. flavicollis individuals (6.7%) than in males (1.5%). Smaller bank vole population coincided with lower (1.2-4.8%) seropositivity in all small rodents, while more abundant bank vole population meant higher (17.9%) total seropositivity. The TBEV focus originally had only Apodemus mice, bank voles appeared later, reached 20.5% positivity and raised the positivity in small rodents from 4% to 10.2% in 3 years. The results highlight the role of M. glareolus and of adult rodents in maintaining the TBEV in nature.
在一个已知的蜱传脑炎病毒 (TBEV) 焦点中捕获的啮齿动物进行了为期 4 年的血清学调查，共进行了 28 次访问。收集的血清通过病毒中和试验进行分析。林姬鼠（Myodes glareolus）对 TBEV 的抗体发生率（20.5%）明显高于黑线姬鼠（Apodemus flavicollis）（3.7%）和黑线仓鼠（Apodemus agrarius）（4.6%）。在所有物种中，成年个体（6.8%）的抗体发生率高于幼体（1.7%）。在 A. flavicollis 个体中，雌性的抗体发生率（6.7%）高于雄性（1.5%）。林姬鼠种群数量较少与所有小型啮齿动物的血清阳性率较低（1.2-4.8%）有关，而林姬鼠种群数量较多则意味着总血清阳性率较高（17.9%）。TBEV 焦点最初只有黑线姬鼠，林姬鼠后来出现，在 3 年内，其阳性率达到 20.5%，使小型啮齿动物的阳性率从 4%提高到 10.2%。研究结果强调了 M. glareolus 和成年啮齿动物在自然界中维持 TBEV 的作用。
