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代谢组学作为营养研究中的一种工具。

Metabolomics as a tool in nutritional research.

作者信息

Gibbons Helena, O'Gorman Aoife, Brennan Lorraine

机构信息

aUCD Conway Institute bUCD Institute of Food and Health, Belfield, Dublin, Ireland.

出版信息

Curr Opin Lipidol. 2015 Feb;26(1):30-4. doi: 10.1097/MOL.0000000000000140.

Abstract

PURPOSE OF REVIEW

Metabolomics is emerging as a powerful tool for studying metabolic processes and in recent years, the applications in the area of nutrition have risen rapidly. The present review gives an overview of the current applications in the field of nutrition and identifies areas in need of advancement.

RECENT FINDINGS

Applications in nutrition research can in general be divided into three main areas: identification of dietary biomarkers, study of diet-related diseases and identification of biomarkers of disease and application to dietary intervention studies as a tool to identify molecular mechanisms.

SUMMARY

Metabolomics has made a significant impact on all the areas identified above and is set to have a major impact on the study of diet-health relationships.

摘要

综述目的

代谢组学正成为研究代谢过程的强大工具,近年来在营养领域的应用迅速增加。本综述概述了营养领域的当前应用,并确定了需要改进的领域。

最新发现

营养研究中的应用一般可分为三个主要领域:膳食生物标志物的鉴定、饮食相关疾病的研究以及疾病生物标志物的鉴定,并作为识别分子机制的工具应用于膳食干预研究。

总结

代谢组学已对上述所有领域产生了重大影响,并将对饮食与健康关系的研究产生重大影响。

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