Okano M, Luka J, Thiele G M, Sakiyama Y, Matsumoto S, Purtilo D T
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68105-1065.
J Clin Microbiol. 1989 Oct;27(10):2379-80. doi: 10.1128/jcm.27.10.2379-2380.1989.
Eighteen of a total of 22 serum specimens (81.8%) from patients with Kawasaki disease were positive for immunoglobulin G or M antibodies to human herpesvirus 6, whereas 10 of 16 age- and sex-matched healthy controls (62.5%) were seropositive. Additionally, increased geometric mean antibody titers of immunoglobulin G were shown in these patients. These results suggest that the status of human herpesvirus 6 infection may be a reflection of the immunologic alterations that are associated with Kawasaki disease.
在22例川崎病患者的血清标本中，有18例（81.8%）针对人疱疹病毒6的免疫球蛋白G或M抗体呈阳性，而在16例年龄和性别匹配的健康对照者中，有10例（62.5%）血清学呈阳性。此外，这些患者的免疫球蛋白G几何平均抗体滴度升高。这些结果表明，人疱疹病毒6感染状态可能反映了与川崎病相关的免疫改变。
