Center for Functional GI and Motility Disorders, University of North Carolina, Chapel Hill, NC.
Department of Pediatrics, Louisiana State University School of Medicine, New Orleans, LA.
J Pediatr. 2015 Mar;166(3):684-9. doi: 10.1016/j.jpeds.2014.11.039. Epub 2014 Dec 31.
To determine the prevalence of gastrointestinal symptoms suggestive of an infant/toddler functional gastrointestinal disorder (FGID) as reported by parents in a representative community sample.
Mothers (n = 320) of children aged 0-3 years old were recruited in the US and completed a questionnaire about their child's and their own gastrointestinal symptoms.
By Rome criteria, 27% of infants/toddlers qualified for FGIDs. Infant regurgitation was the most common disorder in infants and functional constipation in toddlers. No age, sex, or race differences were found in FGID diagnoses. Compared with those who did not meet Rome criteria, toddlers with FGID had lower quality of life (M = 80.1 vs M = 90.3, P < .001), increased medical visits (M = 0.38 vs 0.14; P < .05), mental health visits (M = 0.29 vs 0.06; P < .05), and hospital stays (M = 0.35 vs 0.06; P < .01). A child was more likely to suffer from hard stools if the parent also reported hard stools (P = .02), but similar association was not found with loose stools.
FGIDs are common in infants and toddlers and can be identified in the general population. They do not vary with sex and race. Quality of life is reduced in those with FGIDs. More research is needed into these largely neglected conditions as it may improve the lives of a significant number of young children.
通过父母报告,确定在具有代表性的社区样本中,疑似婴儿/幼儿功能性胃肠疾病(FGID)的胃肠道症状的流行率。
在美国招募了 320 名 0-3 岁儿童的母亲,并让其完成一份关于其子女胃肠道症状及其自身胃肠道症状的问卷。
根据罗马标准,27%的婴儿/幼儿符合 FGID 标准。婴儿反流是婴儿中最常见的疾病,幼儿功能性便秘。FGID 诊断在年龄、性别或种族方面无差异。与不符合罗马标准的儿童相比,患有 FGID 的幼儿生活质量较低(M=80.1 与 M=90.3,P<.001),就诊次数更多(M=0.38 与 M=0.14;P<.05),心理健康就诊次数更多(M=0.29 与 M=0.06;P<.05),住院次数更多(M=0.35 与 M=0.06;P<.01)。如果父母报告有硬便,孩子更有可能出现硬便(P=.02),但与稀便无类似关联。
FGID 在婴儿和幼儿中很常见,可以在普通人群中识别。它们与性别和种族无关。患有 FGID 的儿童生活质量下降。需要对这些被广泛忽视的疾病进行更多研究,因为这可能会改善大量幼儿的生活。