Lewis Meredith L, Palsson Olafur S, Whitehead William E, van Tilburg Miranda A L
University of North Carolina School of Medicine, Chapel Hill, NC.
University of North Carolina School of Medicine, Chapel Hill, NC.
J Pediatr. 2016 Oct;177:39-43.e3. doi: 10.1016/j.jpeds.2016.04.008. Epub 2016 May 4.
To determine the prevalence of functional gastrointestinal (GI) disorders (FGIDs) in children and adolescents in a representative community sample of the US.
The study recruited a general population sample of mothers (n = 949) of children and adolescents aged 4-18 years. Child and adolescent GI symptoms were assessed using parental report through online questionnaires, including the Questionnaire on Pediatric Gastrointestinal Symptoms and the PedsQL4.0 Generic Core Scale. Parental GI symptoms, and demographic characteristics were also assessed. The data was used to determine prevalence of FGIDs.
Using Rome III criteria by parental report, 23.1% of children and adolescents qualified for at least 1 FGID. Functional constipation and abdominal migraine were the most common FGIDs. All 10 child/adolescent FGIDs occurred, except rumination. Significant prevalence differences were not found between sexes, except in functional constipation, which was more prevalent in males than females (P = .022). There were no significant prevalence differences between racial or ethnic groups. Children who met criteria for an FGID had lower quality of life (median = 76.4) than children who did not (median = 89.6; P < .001). Children were more likely to qualify for a FGID if their parent also qualified for a FGID (P < .01).
FGIDs are common in children and adolescents in the US. There are no significant differences in FGIDs between sex, race, or ethnic groups, except in functional constipation. There is overlap between parental and child FGID symptoms. Children with a FGID report a lower quality of life than healthy children.
在美国一个具有代表性的社区样本中，确定儿童和青少年功能性胃肠病（FGIDs）的患病率。
该研究招募了4至18岁儿童和青少年的母亲这一普通人群样本（n = 949）。通过在线问卷由家长报告来评估儿童和青少年的胃肠道症状，包括儿科胃肠道症状问卷和儿童生活质量量表4.0通用核心量表。还评估了家长的胃肠道症状和人口统计学特征。这些数据用于确定FGIDs的患病率。
根据家长报告采用罗马Ⅲ标准，23.1%的儿童和青少年符合至少一种FGID的标准。功能性便秘和腹型偏头痛是最常见的FGIDs。除反刍障碍外，所有10种儿童/青少年FGIDs均有发生。除功能性便秘男性患病率高于女性外（P = 0.022），未发现性别之间存在显著的患病率差异。种族或族裔群体之间也没有显著的患病率差异。符合FGID标准的儿童生活质量（中位数 = 76.4）低于不符合标准的儿童（中位数 = 89.6；P < 0.001）。如果孩子的家长也符合FGID标准，那么孩子更有可能符合FGID标准（P < 0.01）。
FGIDs在美国儿童和青少年中很常见。除功能性便秘外，FGIDs在性别、种族或族裔群体之间没有显著差异。家长和孩子的FGID症状存在重叠。患有FGID的儿童报告的生活质量低于健康儿童。
