McCauley Elizabeth, Gudmundsen Gretchen, Schloredt Kelly, Martell Christopher, Rhew Isaac, Hubley Samuel, Dimidjian Sona
a Seattle Children's Research Institute and University of Washington.
b University of Washington.
J Clin Child Adolesc Psychol. 2016;45(3):291-304. doi: 10.1080/15374416.2014.979933. Epub 2015 Jan 20.
This study aimed to examine implementation feasibility and initial treatment outcomes of a behavioral activation (BA) based treatment for adolescent depression, the Adolescent Behavioral Activation Program (A-BAP). A randomized, controlled trial was conducted with 60 clinically referred adolescents with a depressive disorder who were randomized to receive either 14 sessions of A-BAP or uncontrolled evidenced-based practice for depression. The urban sample was 64% female, predominantly Non-Hispanic White (67%), and had an average age of 14.9 years. Measures of depression, global functioning, activation, and avoidance were obtained through clinical interviews and/or through parent and adolescent self-report at preintervention and end of intervention. Intent-to-treat linear mixed effects modeling and logistic regression analysis revealed that both conditions produced statistically significant improvement from pretreatment to end of treatment in depression, global functioning, and activation and avoidance. There were no significant differences across treatment conditions. These findings provide the first step in establishing the efficacy of BA as a treatment for adolescent depression and support the need for ongoing research on BA as a way to enhance the strategies available for treatment of depression in this population.
本研究旨在检验基于行为激活(BA)的青少年抑郁症治疗方案——青少年行为激活项目(A - BAP)的实施可行性和初始治疗效果。对60名临床诊断为抑郁症的青少年进行了一项随机对照试验,这些青少年被随机分为两组,一组接受14节A - BAP治疗课程,另一组接受无对照的循证抑郁症治疗。该城市样本中64%为女性,主要是非西班牙裔白人(67%),平均年龄为14.9岁。通过临床访谈和/或在干预前及干预结束时由家长和青少年自我报告,获取抑郁症、整体功能、行为激活和回避方面的测量数据。意向性治疗线性混合效应模型和逻辑回归分析显示,两种治疗条件下从治疗前到治疗结束在抑郁症、整体功能、行为激活和回避方面均产生了具有统计学意义的改善。不同治疗条件之间没有显著差异。这些发现为确立行为激活作为青少年抑郁症治疗方法的疗效迈出了第一步,并支持继续开展关于行为激活的研究,以此作为增强该人群抑郁症治疗可用策略的一种方式。