From the Department of Outcomes Research, Cleveland Clinic, Cleveland, Ohio (Z.S., H.H., D.I.S., K.P., L.S., A.K.); Department of Quantitative Health Sciences and Outcomes Research, Cleveland Clinic, Cleveland, Ohio (J.E.D., D.Y.); and Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio (A.F.D., V.S.). Current affiliations: Anesthesiology and Perioperative Medicine, Georgia Regent University, Augusta, Georgia (Z.S.); and Department of Anesthesiology, Faculty of Medicine, Chiang Mai University, Chiangmai, Thailand (K.P.).
Anesthesiology. 2015 Feb;122(2):276-85. doi: 10.1097/ALN.0000000000000551.
Core temperature patterns in patients warmed with forced air remain poorly characterized. Also unknown is the extent to which transient and mild intraoperative hypothermia contributes to adverse outcomes in broad populations.
We evaluated esophageal (core) temperatures in 58,814 adults having surgery lasting >60 min who were warmed with forced air. Independent associations between hypothermic exposure and transfusion requirement and duration of hospitalization were evaluated.
In every percentile subgroup, core temperature decreased during the first hour and subsequently increased. The mean lowest core temperature during the first hour was 35.7 ± 0.6°C. Sixty-four percent of the patients reached a core temperature threshold of <36°C 45 min after induction; 29% reached a core temperature threshold of <35.5°C. Nearly half the patients had continuous core temperatures <36°C for more than an hour, and 20% of the patients were <35.5°C for more than an hour. Twenty percent of patients had continuous core temperatures <36°C for more than 2 h, and 8% of the patients were below 35.5°C for more than 2 h. Hypothermia was independently associated with both transfusions and duration of hospitalization, although the prolongation of hospitalization was small.
Even in actively warmed patients, hypothermia is routine during the first hour of anesthesia. Thereafter, average core temperatures progressively increase. Nonetheless, intraoperative hypothermia was common, and often prolonged. Hypothermia was associated with increased transfusion requirement, which is consistent with numerous randomized trials.
采用强制空气加热的患者的核心温度模式仍描述不足。也不知道在广泛的人群中,短暂和轻度的术中低体温对不良结局的影响程度。
我们评估了 58814 名接受超过 60 分钟手术且采用强制空气加热的成年人的食管(核心)温度。评估了低体温暴露与输血需求以及住院时间之间的独立关联。
在每个百分位亚组中,核心温度在第一个小时内下降,随后升高。第一个小时内的平均最低核心温度为 35.7 ± 0.6°C。64%的患者在诱导后 45 分钟达到<36°C 的核心温度阈值;29%达到<35.5°C 的核心温度阈值。近一半的患者连续核心温度<36°C 超过 1 小时,20%的患者连续核心温度<35.5°C 超过 1 小时。20%的患者连续核心温度<36°C 超过 2 小时,8%的患者连续核心温度<35.5°C 超过 2 小时。低体温与输血和住院时间均独立相关,尽管住院时间延长很小。
即使在积极加热的患者中,麻醉的第一个小时内也会出现常规低体温。此后,平均核心温度逐渐升高。尽管如此,术中低体温仍然很常见,且往往持续时间较长。低体温与输血需求增加有关,这与许多随机试验一致。