Adamowski Maciek, Friml Jiří
Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria.
Institute of Science and Technology Austria, 3400 Klosterneuburg, Austria
Plant Cell. 2015 Jan;27(1):20-32. doi: 10.1105/tpc.114.134874. Epub 2015 Jan 20.
Auxin participates in a multitude of developmental processes, as well as responses to environmental cues. Compared with other plant hormones, auxin exhibits a unique property, as it undergoes directional, cell-to-cell transport facilitated by plasma membrane-localized transport proteins. Among them, a prominent role has been ascribed to the PIN family of auxin efflux facilitators. PIN proteins direct polar auxin transport on account of their asymmetric subcellular localizations. In this review, we provide an overview of the multiple developmental roles of PIN proteins, including the atypical endoplasmic reticulum-localized members of the family, and look at the family from an evolutionary perspective. Next, we cover the cell biological and molecular aspects of PIN function, in particular the establishment of their polar subcellular localization. Hormonal and environmental inputs into the regulation of PIN action are summarized as well.
生长素参与多种发育过程以及对环境信号的响应。与其他植物激素相比，生长素具有独特的特性，因为它通过质膜定位的转运蛋白促进进行定向的细胞间运输。其中，生长素外排促进因子的PIN家族发挥了突出作用。PIN蛋白因其不对称的亚细胞定位而指导生长素的极性运输。在这篇综述中，我们概述了PIN蛋白的多种发育作用，包括该家族中非典型的内质网定位成员，并从进化的角度审视该家族。接下来，我们阐述PIN功能的细胞生物学和分子层面，特别是其极性亚细胞定位的建立。我们还总结了激素和环境对PIN作用调控的影响。
