García Juan Antonio, Pallás Vicente
Centro Nacional de Biotecnología-CSIC, Campus de la Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Instituto de Biología Molecular y Celular de las Plantas (CSIC-Universidad Politécnica de Valencia), Avenida de los Naranjos s/n, 46022 Valencia, Spain.
Curr Opin Virol. 2015 Apr;11:21-30. doi: 10.1016/j.coviro.2015.01.001. Epub 2015 Jan 23.
Plant viruses must usurp host factors/routes for their survival. Disturbances derived from this extreme dependence for host resources, together with physiological alterations associated with defensive responses, can cause, in some virus-host combinations, acute or chronic plant diseases. As the coding capacity of these biotrophic pathogens is limited, viral-encoded proteins must essentially be multifunctional proteins involved in very different steps of their life cycle, and are usually elicitors of defensive responses. Thus, most, if not all, viral-encoded proteins can act as pathogenicity determinants. Indeed, the viral proteins involved in the essential processes of their life cycle, such as replication, movement, encapsidation and transmission can be critical players of the pathogenesis process through direct or indirect interactions. This review updates our knowledge on how viral factors affect plant physiology and contribute to the development of symptomatology.
植物病毒必须夺取宿主因子/途径以维持生存。这种对宿主资源的极端依赖所产生的干扰，连同与防御反应相关的生理变化，在某些病毒-宿主组合中，可能导致急性或慢性植物病害。由于这些专性寄生病原体的编码能力有限，病毒编码的蛋白质本质上必须是参与其生命周期非常不同阶段的多功能蛋白质，并且通常是防御反应的诱导物。因此，大多数（如果不是全部）病毒编码的蛋白质都可以作为致病性决定因素。事实上，参与病毒生命周期基本过程（如复制、移动、衣壳化和传播）的病毒蛋白，通过直接或间接相互作用，可能是发病机制过程的关键参与者。这篇综述更新了我们对病毒因子如何影响植物生理并导致症状发展的认识。
