Ernst Aurélie, Frisén Jonas
Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.
PLoS Biol. 2015 Jan 26;13(1):e1002045. doi: 10.1371/journal.pbio.1002045. eCollection 2015 Jan.
New neurons are continuously generated in specific regions in the adult brain. Studies in rodents have demonstrated that adult-born neurons have specific functional features and mediate neural plasticity. Data on the extent and dynamics of adult neurogenesis in adult humans are starting to emerge, and there are clear similarities and differences compared to other mammals. Why do these differences arise? And what do they mean?
在成人大脑中,特定区域会持续产生新的神经元。对啮齿动物的研究表明,成年后生成的神经元具有特定的功能特征,并介导神经可塑性。关于成年人类大脑中成年神经发生的程度和动态的数据开始出现,与其他哺乳动物相比,存在明显的异同。这些差异为何会出现?又意味着什么?