Tavakoli Javad, Miar Solaleh, Majid Zadehzare Mohammad, Akbari Hossein
Dept. of Biomedical Engineering, Biomedical Engineering Faculty, Science and Research Branch of Islamic Azad University, Tehran, Iran.
Iran J Cancer Prev. 2012 Summer;5(3):144-56.
Based on a common belief, herbal medicine with the least possible side effects should be the center of attention in cancer care; however, in many cases they have not been properly studied with reliable clinical trials in human subjects. In this review, it was attempted to identify the available evidence on the use and clinical effects of herbs in cancer care. The research consists of two major parts including immunomodulator and chemopreventive herbal compounds whose mechanism, biological response, anticancer element of extract and related benefits were completely studied. Also, the safety of herbal anticancer compounds was discussed. Although the use of herbal medicines in treating cancer shows less chemotherapy-induced, toxicity, more researches are required to reach their full therapeutic potentials.
基于一种普遍的观念,副作用尽可能小的草药应该成为癌症治疗关注的核心;然而,在许多情况下,它们尚未在人体受试者中通过可靠的临床试验进行充分研究。在本综述中,试图确定关于草药在癌症治疗中的使用和临床效果的现有证据。该研究包括两个主要部分,即免疫调节剂和化学预防草药化合物,对其作用机制、生物学反应、提取物的抗癌成分及相关益处进行了全面研究。此外,还讨论了草药抗癌化合物的安全性。尽管草药在治疗癌症方面显示出比化疗引起的毒性更小,但仍需要更多研究来充分发挥其治疗潜力。