• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肠道检查:分子检测时代艰难梭菌的检测与治疗

Gut check: Clostridium difficile testing and treatment in the molecular testing era.

作者信息

Buckel Whitney R, Avdic Edina, Carroll Karen C, Gunaseelan Vidhya, Hadhazy Eric, Cosgrove Sara E

机构信息

1Intermountain Healthcare,Intermountain Medical Center,Murray,Utah.

2Johns Hopkins Health System,The Johns Hopkins Hospital,Baltimore,Maryland.

出版信息

Infect Control Hosp Epidemiol. 2015 Feb;36(2):217-21. doi: 10.1017/ice.2014.19.

DOI:10.1017/ice.2014.19
PMID:25633006
Abstract

We evaluated the impact of nursing education and stewardship interventions on Clostridium difficile testing and treatment appropriateness. Diarrhea documentation increased for those with positive tests (45% to 70%); pretreatment laxative use decreased (50% to 19%). Appropriate treatment increased for severe infection (57% to 93%), but all asymptomatically colonized patients were treated.

摘要

我们评估了护理教育和管理干预措施对艰难梭菌检测及治疗合理性的影响。检测呈阳性者的腹泻记录有所增加(从45%增至70%);治疗前泻药的使用有所减少(从50%降至19%)。重症感染的合理治疗有所增加(从57%增至93%),但所有无症状定植患者均接受了治疗。

相似文献

1
Gut check: Clostridium difficile testing and treatment in the molecular testing era.肠道检查:分子检测时代艰难梭菌的检测与治疗
Infect Control Hosp Epidemiol. 2015 Feb;36(2):217-21. doi: 10.1017/ice.2014.19.
2
Clostridium difficile in adult patients with nosocomial diarrhea in a Costa Rican hospital.哥斯达黎加一家医院成年医院获得性腹泻患者中的艰难梭菌
Am J Trop Med Hyg. 2008 Aug;79(2):164-5.
3
Clostridium difficile: progress and challenges.艰难梭菌:进展与挑战。
Ann N Y Acad Sci. 2010 Dec;1213:62-9. doi: 10.1111/j.1749-6632.2010.05863.x.
4
Laboratory diagnosis of antibiotic-associated diarrhea: a Polish pilot study into the clinical relevance of Clostridium difficile and Clostridium perfringens toxins.抗生素相关性腹泻的实验室诊断:一项关于艰难梭菌和产气荚膜梭菌毒素临床相关性的波兰试点研究。
Diagn Microbiol Infect Dis. 2007 May;58(1):71-5. doi: 10.1016/j.diagmicrobio.2006.12.007. Epub 2007 Feb 14.
5
Rapid diagnosis of toxinogenic Clostridium difficile in faecal samples with internally controlled real-time PCR.采用内控实时聚合酶链反应对粪便样本中产生毒素的艰难梭菌进行快速诊断。
Clin Microbiol Infect. 2006 Feb;12(2):184-6. doi: 10.1111/j.1469-0691.2005.01301.x.
6
Repeat Clostridium difficile Testing.重复艰难梭菌检测。
JAMA. 2016 Dec 13;316(22):2422-2423. doi: 10.1001/jama.2016.17173.
7
Lack of value of repeat stool testing for Clostridium difficile toxin.艰难梭菌毒素重复粪便检测的价值缺失
Am J Med. 2006 Apr;119(4):356.e7-8. doi: 10.1016/j.amjmed.2005.08.026.
8
Impact of toxigenic Clostridium difficile polymerase chain reaction testing on the clinical microbiology laboratory and inpatient epidemiology.产毒艰难梭菌聚合酶链反应检测对临床微生物学实验室和住院患者流行病学的影响。
Diagn Microbiol Infect Dis. 2013 Aug;76(4):534-8. doi: 10.1016/j.diagmicrobio.2013.04.020. Epub 2013 Jun 2.
9
Infection with Toxin A-Negative, Toxin B-Negative, Binary Toxin-Positive Clostridium difficile in a Young Patient with Ulcerative Colitis.一名患有溃疡性结肠炎的年轻患者感染了毒素A阴性、毒素B阴性、二元毒素阳性的艰难梭菌。
J Clin Microbiol. 2015 Nov;53(11):3702-4. doi: 10.1128/JCM.01810-15. Epub 2015 Sep 9.
10
Chapter 2-12-7. Anaerobic infections (individual fields): antibiotic-associated diarrhea and enterocolitis.第2-12-7章。厌氧感染(各领域):抗生素相关性腹泻和小肠结肠炎。
J Infect Chemother. 2011 Jul;17 Suppl 1:137-9. doi: 10.1007/s10156-010-0160-7.

引用本文的文献

1
A mixed-methods study assessing the performance of a clinical decision support tool for testing for patients receiving laxatives.一项混合方法研究,评估一种用于接受泻药治疗患者检测的临床决策支持工具的性能。
Infect Control Hosp Epidemiol. 2025 Mar 13;46(5):1-7. doi: 10.1017/ice.2025.30.
2
Curbing inappropriate treatment in patients receiving concomitant laxatives.遏制接受缓泻剂的患者的不适当治疗。
Antimicrob Steward Healthc Epidemiol. 2025 Feb 17;5(1):e50. doi: 10.1017/ash.2025.25. eCollection 2025.
3
Overview of current detection methods and microRNA potential in infection screening.
感染筛查中当前检测方法和 microRNA 潜力概述。
World J Gastroenterol. 2023 Jun 14;29(22):3385-3399. doi: 10.3748/wjg.v29.i22.3385.
4
Prospective Review of Testing Indications to Inform Local Laboratory Stewardship Initiatives.为指导当地实验室管理举措而对检测指征进行的前瞻性评估。
Infect Prev Pract. 2019 Aug 5;1(2):100017. doi: 10.1016/j.infpip.2019.100017. eCollection 2019 Jun.
5
The Role of Diagnostic Stewardship in Testing: Challenges and Opportunities.诊断管理在检测中的作用:挑战与机遇
Curr Infect Dis Rep. 2020 Mar;22(3). doi: 10.1007/s11908-020-0715-4. Epub 2020 Feb 17.
6
Recent advances in the treatment of infection: the ever-changing guidelines.感染治疗的最新进展:不断变化的指南。
Fac Rev. 2020 Nov 18;9:13. doi: 10.12703/b/9-13. eCollection 2020.
7
Randomized Controlled Trial of Oral Vancomycin Treatment in Clostridioides difficile-Colonized Patients.口服万古霉素治疗艰难梭菌定植患者的随机对照试验。
mSphere. 2021 Jan 13;6(1):e00936-20. doi: 10.1128/mSphere.00936-20.
8
Improving Appropriate Diagnosis of Infection Through an Enteric Pathogen Order Set With Computerized Clinical Decision Support: An Interrupted Time Series Analysis.通过带有计算机化临床决策支持的肠道病原体医嘱集改善感染的恰当诊断:一项中断时间序列分析
Open Forum Infect Dis. 2020 Aug 21;7(10):ofaa366. doi: 10.1093/ofid/ofaa366. eCollection 2020 Oct.
9
Using diagnostic stewardship to reduce rates, healthcare expenditures and accurately identify cases of hospital-onset infection.运用诊断管理来降低比率、医疗支出,并准确识别医院获得性感染病例。
Infect Control Hosp Epidemiol. 2021 Jan;42(1):51-56. doi: 10.1017/ice.2020.375. Epub 2020 Sep 18.
10
Ultrasensitive Clostridioides difficile Toxin Testing for Higher Diagnostic Accuracy.用于提高诊断准确性的超敏艰难梭菌毒素检测
J Clin Microbiol. 2020 May 26;58(6). doi: 10.1128/JCM.01913-19.