A split-Cas9 architecture for inducible genome editing and transcription modulation.
作者信息
Zetsche Bernd, Volz Sara E, Zhang Feng
机构信息
1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [2] McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [3] Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge Massachusetts, USA. [4] Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge Massachusetts, USA. [5] Department of Developmental Pathology, Institute of Pathology, Bonn Medical School, Bonn, Germany.
1] Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. [2] McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. [3] Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge Massachusetts, USA. [4] Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge Massachusetts, USA.
出版信息
Nat Biotechnol. 2015 Feb;33(2):139-42. doi: 10.1038/nbt.3149.
Abstract
摘要
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