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双相谱系障碍中的极端认知:与人格障碍特征及发作复发风险的关联

Extreme cognitions in bipolar spectrum disorders: associations with personality disorder characteristics and risk for episode recurrence.

作者信息

Stange Jonathan P, Adams Ashleigh Molz, O'Garro-Moore Jared K, Weiss Rachel B, Ong Mian-Li, Walshaw Patricia D, Abramson Lyn Y, Alloy Lauren B

机构信息

Temple University.

McLean Hospital and Harvard Medical School.

出版信息

Behav Ther. 2015 Mar;46(2):242-56. doi: 10.1016/j.beth.2014.09.003. Epub 2014 Sep 19.

Abstract

Bipolar spectrum disorders (BSDs) are often characterized by cognitive inflexibility and affective extremities, including "extreme" or polarized thoughts and beliefs, which have been shown to predict a more severe course of illness. However, little research has evaluated factors that may be associated with extreme cognitions, such as personality disorders, which are often characterized by extreme, inflexible beliefs and are also associated with poor illness course in BSDs. The present study evaluated associations among BSDs, personality disorder characteristics, and extreme cognitions (polarized responses made on measures of attributional style and dysfunctional attitudes), as well as links between extreme cognitions and the occurrence of mood episodes, among euthymic young adults with BSDs (n=83) and demographically matched healthy controls (n=89) followed prospectively for 3years. The relationship between personality disorder characteristics and negative and positive extreme cognitions was stronger among BSD participants than among healthy controls, even after statistically accounting for general cognitive styles. Furthermore, extreme negative cognitions predicted the prospective onset of major depressive and hypomanic episodes. These results suggest that extreme cognitive styles are most common in individuals with BSDs and personality disorder characteristics, and they provide further evidence that extreme negative cognitions may confer risk for mood dysregulation.

摘要

双相谱系障碍(BSDs)通常具有认知灵活性不足和情感极端化的特点,包括“极端”或两极化的思维与信念,这些已被证明可预测病情的更严重发展。然而,很少有研究评估可能与极端认知相关的因素,如人格障碍,人格障碍通常以极端、僵化的信念为特征,且也与双相谱系障碍的不良病程相关。本研究评估了双相谱系障碍、人格障碍特征与极端认知(在归因风格和功能失调态度测量中做出的两极化反应)之间的关联,以及在83名双相谱系障碍的心境正常年轻成年人和89名人口统计学匹配的健康对照者中,极端认知与情绪发作发生之间的联系,对他们进行了为期3年的前瞻性随访。即使在对一般认知风格进行统计学校正之后,双相谱系障碍参与者中人格障碍特征与消极和积极极端认知之间的关系仍比健康对照者更强。此外,极端消极认知可预测重度抑郁发作和轻躁狂发作的前瞻性发生。这些结果表明,极端认知风格在双相谱系障碍患者和人格障碍特征的个体中最为常见,并且它们进一步证明极端消极认知可能带来情绪失调的风险。

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