Center for Alcohol and Addiction Studies and the Department of Behavioral and Social Sciences, Brown University School of Public Health, Providence, RI;
Department of Psychology, Hiram College, Hiram, OH;
Nicotine Tob Res. 2015 Nov;17(11):1385-92. doi: 10.1093/ntr/ntv011. Epub 2015 Feb 2.
Greater depressive symptoms and low positive affect (PA) are associated with poor smoking cessation outcomes. Smoking cessation approaches that incorporate a focus on PA may benefit smokers trying to quit. The purpose of this study was to conduct a pilot randomized clinical trial to compare standard smoking cessation treatment (ST) with smoking cessation treatment that targets positive affect, termed positive psychotherapy for smoking cessation (PPT-S).
Smokers who were seeking smoking cessation treatment were assigned by urn randomization to receive, along with 8 weeks of nicotine replacement therapy, either ST (n = 31) or PPT-S (n = 35). Seven-day point prevalence smoking abstinence was biochemically confirmed at 8, 16, and 26 weeks.
Compared to ST, a greater percentage of participants in PPT-S were abstinent at 8 weeks, 16 weeks, and 26 weeks, but these differences were nonsignificant. In a more statistically powerful longitudinal model, participants in PPT-S had a significantly higher odds of abstinence (adjusted odds ratio [AOR] = 2.75; 95% CI = 1.02, 7.42; p = .046) across follow-ups compared to those in ST. The positive effect of PPT-S was stronger for those higher in PA (OR = 6.69, 95% CI = 1.16, 38.47, p = .03). Greater use of PPT-S strategies during the initial 8 weeks of quitting was associated with a less steep decline in smoking abstinence rates over time (OR = 2.64, 95% CI = 1.06, 6.56, p =.04).
This trial suggests substantial promise for incorporating PPT into smoking cessation treatment.
抑郁症状和低正性情绪与较差的戒烟效果相关。将关注正性情绪纳入戒烟治疗的戒烟方法可能使试图戒烟的吸烟者受益。本研究旨在进行一项试点随机临床试验，比较标准戒烟治疗（ST）与旨在改善正性情绪的戒烟治疗（称为戒烟正性心理治疗，PPT-S）。
正在寻求戒烟治疗的吸烟者通过 urn 随机分配，接受 8 周尼古丁替代治疗，同时接受 ST（n = 31）或 PPT-S（n = 35）治疗。在第 8、16 和 26 周，通过生物化学方法确认 7 天点患病率的戒烟情况。
与 ST 相比，PPT-S 组在第 8、16 和 26 周时的戒烟率更高，但差异无统计学意义。在更具统计学效力的纵向模型中，与 ST 相比，PPT-S 组的参与者在随访期间的戒烟可能性显著更高（调整后的优势比[OR] = 2.75；95%CI = 1.02,7.42；p =.046）。对于正性情绪更高的人，PPT-S 的积极效果更强（OR = 6.69，95%CI = 1.16,38.47，p =.03）。在戒烟的最初 8 周内更频繁地使用 PPT-S 策略与随着时间的推移戒烟率下降幅度变缓相关（OR = 2.64，95%CI = 1.06,6.56，p =.04）。
这项试验表明，将 PPT 纳入戒烟治疗具有很大的潜力。
