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2012/2013年12个欧洲国家流感病毒型别和亚型分布的年龄特异性差异。

Age-specific differences in influenza virus type and subtype distribution in the 2012/2013 season in 12 European countries.

作者信息

Beauté J, Zucs P, Korsun N, Bragstad K, Enouf V, Kossyvakis A, Griškevičius A, Olinger C M, Meijer A, Guiomar R, Prosenc K, Staroňová E, Delgado C, Brytting M, Broberg E

机构信息

European Centre for Disease Prevention and Control (ECDC),Solna,Sweden.

National Centre of Infectious and Parasitic Diseases,Sofia,Bulgaria.

出版信息

Epidemiol Infect. 2015 Oct;143(14):2950-8. doi: 10.1017/S0950268814003422. Epub 2015 Feb 4.

DOI:10.1017/S0950268814003422
PMID:25648399
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4595855/
Abstract

The epidemiology of seasonal influenza is influenced by age. During the influenza season, the European Influenza Surveillance Network (EISN) reports weekly virological and syndromic surveillance data [mostly influenza-like illness (ILI)] based on national networks of sentinel primary-care providers. Aggregated numbers by age group are available for ILI, but not linked to the virological data. At the end of the influenza season 2012/2013, all EISN laboratories were invited to submit a subset of their virological data for this season, including information on age. The analysis by age group suggests that the overall distribution of circulating (sub)types may mask substantial differences between age groups. Thus, in cases aged 5-14 years, 75% tested positive for influenza B virus whereas all other age groups had an even distribution of influenza A and B viruses. This means that the intepretation of syndromic surveillance data without age group-specific virological data may be misleading. Surveillance at the European level would benefit from the reporting of age-specific influenza data.

摘要

季节性流感的流行病学受年龄影响。在流感季节,欧洲流感监测网络(EISN)基于全国哨点基层医疗服务提供者网络,每周报告病毒学和症状监测数据[主要是流感样疾病(ILI)]。可获得按年龄组汇总的ILI病例数,但未与病毒学数据关联。在2012/2013流感季节结束时,邀请所有EISN实验室提交该季节的部分病毒学数据,包括年龄信息。按年龄组分析表明,流行(亚)型的总体分布可能掩盖了年龄组之间的显著差异。因此,在5 - 14岁的病例中,75%的人检测出乙型流感病毒呈阳性,而所有其他年龄组甲型和乙型流感病毒的分布较为均匀。这意味着在没有特定年龄组病毒学数据的情况下,对症状监测数据的解读可能会产生误导。欧洲层面的监测将受益于特定年龄流感数据的报告。

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