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怀孕与皮肤。

Pregnancy and skin.

作者信息

Vora Rita V, Gupta Rajat, Mehta Malay J, Chaudhari Arvind H, Pilani Abhishek P, Patel Nidhi

机构信息

Department of Skin and VD, Pramukhswami Medical College and Shree Krishna Hospital, Gujarat, India.

出版信息

J Family Med Prim Care. 2014 Oct-Dec;3(4):318-24. doi: 10.4103/2249-4863.148099.

DOI:10.4103/2249-4863.148099
PMID:25657937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4311336/
Abstract

Pregnancy is associated with complex of endocrinological, immunological, metabolic, and vascular changes that may influence the skin and other organs in various ways. Pregnancy is a period in which more than 90% women have significant and complex skin changes that may have great impact on the woman's life. The dermatoses of pregnancy represent a heterogeneous group of skin diseases related to pregnancy and/or the postpartum period. The dermatoses of pregnancy can be classified into the following three groups: Physiologic skin changes in pregnancy, pre-existing dermatoses affected by pregnancy, and specific dermatoses of pregnancy. Though most of these skin dermatoses are benign and resolve in postpartum period, a few can risk fetal life and require antenatal surveillance. Most of the dermatoses of pregnancy can be treated conservatively but a few require intervention in the form of termination of pregnancy. Correct diagnosis is essential for the treatment of these disorders. This article discusses the current knowledge of various skin changes during pregnancy and the evaluation of the patient with pregnancy dermatoses with special emphasis on clinical features, diagnostic tests, maternal and fetal prognosis, therapy, and management.

摘要

妊娠与一系列内分泌、免疫、代谢及血管变化相关,这些变化可能以多种方式影响皮肤及其他器官。妊娠期间,超过90%的女性会出现显著且复杂的皮肤变化,这可能对其生活产生重大影响。妊娠皮肤病是一组与妊娠和/或产后时期相关的异质性皮肤病。妊娠皮肤病可分为以下三组:妊娠生理性皮肤变化、妊娠影响的既往存在的皮肤病、妊娠特异性皮肤病。尽管这些皮肤疾病大多为良性且在产后会消退,但少数可能危及胎儿生命,需要进行产前监测。大多数妊娠皮肤病可采用保守治疗,但少数需要以终止妊娠的方式进行干预。正确诊断对于这些疾病的治疗至关重要。本文讨论了妊娠期间各种皮肤变化的现有知识以及对妊娠皮肤病患者的评估,特别强调了临床特征、诊断测试、母婴预后、治疗及管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c17/4311336/ec73d2670606/JFMPC-3-318-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c17/4311336/60642dc8a842/JFMPC-3-318-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c17/4311336/ec73d2670606/JFMPC-3-318-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c17/4311336/60642dc8a842/JFMPC-3-318-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c17/4311336/ec73d2670606/JFMPC-3-318-g005.jpg

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本文引用的文献

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Pregnancy and skin.怀孕与皮肤。
J Obstet Gynaecol India. 2012 Jun;62(3):268-75. doi: 10.1007/s13224-012-0179-z. Epub 2012 Aug 28.
2
Specific dermatoses of pregnancy: a review.
West Afr J Med. 2011 Jul-Aug;30(4):239-44.
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Dermatoses of pregnancy - clues to diagnosis, fetal risk and therapy.妊娠期皮肤病——诊断线索、胎儿风险及治疗方法
Ann Dermatol. 2011 Aug;23(3):265-75. doi: 10.5021/ad.2011.23.3.265. Epub 2011 Aug 6.
Cureus. 2024 Sep 23;16(9):e69986. doi: 10.7759/cureus.69986. eCollection 2024 Sep.
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Prevention of Melasma During Pregnancy: Risk Factors and Photoprotection-Focused Strategies.孕期黄褐斑的预防:风险因素及以光防护为重点的策略
Clin Cosmet Investig Dermatol. 2024 Oct 15;17:2301-2310. doi: 10.2147/CCID.S488663. eCollection 2024.
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Melanoma in Pregnancy-Diagnosis, Treatment, and Consequences for Fetal Development and the Maintenance of Pregnancy.妊娠期黑色素瘤——诊断、治疗及对胎儿发育和维持妊娠的影响
Cancers (Basel). 2024 Jun 7;16(12):2173. doi: 10.3390/cancers16122173.
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Assessment of target organ damage in hypertensive pregnancy.妊娠期高血压疾病靶器官损害的评估
Eur J Prev Cardiol. 2024 Jan 5;31(1):75-76. doi: 10.1093/eurjpc/zwad319.
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Interrelationships between Skin Structure, Function, and Microbiome of Pregnant Females and Their Newborns: Study Protocol for a Prospective Cohort Study.孕妇及其新生儿的皮肤结构、功能与微生物群之间的相互关系:一项前瞻性队列研究的研究方案
Dermatol Res Pract. 2021 Nov 17;2021:4163705. doi: 10.1155/2021/4163705. eCollection 2021.
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A Clinician's Guide to Topical Retinoids.《外用维 A 酸治疗临床指南》
J Cutan Med Surg. 2022 Jan-Feb;26(1):71-78. doi: 10.1177/12034754211035091. Epub 2021 Jul 22.
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Lipidomic analysis of facial skin surface lipid reveals the causes of pregnancy-related skin barrier weakness.面部皮肤表面脂质的脂质组学分析揭示了与妊娠相关的皮肤屏障脆弱的原因。
Sci Rep. 2021 Feb 5;11(1):3229. doi: 10.1038/s41598-021-82624-3.
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The anti-clockwise spiralization of the linea nigra sign.黑线征逆时针螺旋化。
Einstein (Sao Paulo). 2020 Nov 6;18:eAO5432. doi: 10.31744/einstein_journal/2020AO5432. eCollection 2020.
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Pemphigus and pregnancy: a 23-year experience.天疱疮与妊娠:23 年经验。
Indian J Dermatol Venereol Leprol. 2011 Jul-Aug;77(4):534. doi: 10.4103/0378-6323.82404.
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Pemphigoid gestationis: clinical and laboratory evaluation.妊娠疱疹:临床和实验室评估。
Clinics (Sao Paulo). 2009;64(11):1043-7. doi: 10.1590/S1807-59322009001100002.
6
The dermatoses of pregnancy.妊娠期皮肤病
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7
Psoriasis in pregnancy: a review of most important literature data.
Acta Dermatovenerol Croat. 2009;17(3):193-7.
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Intrahepatic cholestasis of pregnancy.妊娠期肝内胆汁淤积症
World J Gastroenterol. 2009 May 7;15(17):2049-66. doi: 10.3748/wjg.15.2049.
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Dermatoses of pregnancy.妊娠皮肤病
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Indian J Dermatol Venereol Leprol. 2007 Mar-Apr;73(2):141. doi: 10.4103/0378-6323.31910.