Khil Laura, Wellmann Jürgen, Berger Klaus
Institute of Epidemiology and Social Medicine, University of Münster, Domagkstraße 3, 48149, Münster, Germany,
Qual Life Res. 2015 Sep;24(9):2099-103. doi: 10.1007/s11136-015-0941-7. Epub 2015 Feb 11.
To analyse the impact of single/combined sensory impairment on health-related quality of life (HRQOL).
Data from 1102 participants (mean age = 51.4 years) of the Dortmund Health Study were analysed. HRQOL was assessed by the Short Form 36 Health Survey (SF-36). Sensory impairment was measured with validated tests. Each impairment variable was coded into four categories (no impairment, mild, moderate, and severe impairment). Data were analysed with general linear models adjusted for possible confounders. The reference category was the group of no sensory impairment.
Sensory impairments did not influence the mental component score (MCS). Severe auditory impairment (-3.7, 95 % CI -6.3, -1.2) and olfactory impairment (-3.3, 95 % CI -5.6, -1.1) were related to a reduction in the physical component score (PCS). Auditory plus visual and gustatory plus visual impairments had a stronger effect on PCS than the respective impairments alone. For most of the other impairment combinations, additive effects were observed.
Sensory impairments reduced self-reported physical but not mental health scores. Combined sensory impairment worsened the impact of single sensory impairment on health.
分析单一/合并感觉障碍对健康相关生活质量（HRQOL）的影响。
对多特蒙德健康研究中1102名参与者（平均年龄=51.4岁）的数据进行分析。采用简短健康调查问卷（SF-36）评估HRQOL。通过经过验证的测试测量感觉障碍。每个障碍变量被编码为四类（无障碍、轻度、中度和重度障碍）。使用针对可能的混杂因素进行调整的一般线性模型分析数据。参考类别为无感觉障碍组。
感觉障碍不影响心理成分得分（MCS）。重度听觉障碍（-3.7，95%CI -6.3，-1.2）和嗅觉障碍（-3.3，95%CI -5.6，-1.1）与身体成分得分（PCS）降低有关。听觉加视觉和味觉加视觉障碍对PCS的影响比各自单独的障碍更强。对于大多数其他障碍组合，观察到相加效应。
感觉障碍降低了自我报告的身体但非心理健康得分。合并感觉障碍加剧了单一感觉障碍对健康的影响。
