He Ying, Wu Hongmiao, Toste F Dean
Institute of Chemistry and BioMedical Sciences, Nanjing University Nanjing, 210046 (China) ; Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, (USA).
Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, (USA).
Chem Sci. 2015 Feb;6(2):1194-1198. doi: 10.1039/C4SC03092C.
A new method for the P-arylation of aryldiazonium salts with H-phosphonates dual gold and photoredox catalysis is described. The reaction proceeds smoothly at room temperature in the absence of base and/or additives, and offers an efficient approach to arylphosphonates. The reaction is proposed to proceed through a photoredox-promoted generation of an electrophilic arylgold(III) intermediate that undergoes coupling with the H-phosphonate nucleophile.
描述了一种利用双金和光氧化还原催化使芳基重氮盐与H-膦酸酯进行P-芳基化的新方法。该反应在室温下无碱和/或添加剂的情况下顺利进行,并为芳基膦酸酯提供了一种有效的合成方法。该反应被认为是通过光氧化还原促进生成亲电芳基金(III)中间体,该中间体与H-膦酸酯亲核试剂发生偶联。