Gurung Sarah P, Schwarz Christine, Hall James P, Cardin Christine J, Brazier John A
Department of Chemistry, University of Reading, Whiteknights, Reading, Berks RG6 6AD, UK.
Chem Commun (Camb). 2015 Apr 4;51(26):5630-2. doi: 10.1039/c4cc07279k.
Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.
利用紫外光谱和同步辐射圆二色光谱发现,i-基序结构内的环长度对热稳定性和pH稳定性均很重要,但与之前的说法相反,较短的环表现出最高的稳定性。