Sabale Sandip, Jadhav Vidhya, Khot Vishwajeet, Zhu Xiaoli, Xin Meiling, Chen Hongxia
Laboratory of Biosensing Technology, School of Life Sciences, Shanghai University, Shanghai, 200444, People's Republic of China,
J Mater Sci Mater Med. 2015 Mar;26(3):127. doi: 10.1007/s10856-015-5466-7. Epub 2015 Feb 18.
Superparamagnetic nanoferrites are prepared by simple and one step refluxing in polyol synthesis. The ferrite nanoparticles prepared by this method exhibit particle sizes below 10 nm and high degree of crystallinity. These ferrite nanoparticles are compared by means of their magnetic properties, induction heating and cell viability studies for its application in magnetic fluid hyperthermia. Out of all studied nanoparticles in present work, only ZnFe2O4 and CoFe2O4 MNPs are able to produce threshold hyperthermia temperature. This rise in temperature is discussed in detail in view of their magneto-structural properties. Therefore ZnFe2O4 and CoFe2O4 MNPs with improved stability, magnetic induction heating and cell viability are suitable candidates for magnetic hyperthermia.
超顺磁性纳米铁氧体通过多元醇合成中的简单一步回流法制备。用这种方法制备的铁氧体纳米颗粒粒径小于10 nm，且结晶度高。通过对这些铁氧体纳米颗粒的磁性、感应加热和细胞活力进行研究，以比较它们在磁流体热疗中的应用。在目前工作中所有研究的纳米颗粒中，只有ZnFe2O4和CoFe2O4磁性纳米颗粒能够产生阈值热疗温度。鉴于它们的磁结构性质，对温度的升高进行了详细讨论。因此，具有改善的稳定性、磁感应加热和细胞活力的ZnFe2O4和CoFe2O4磁性纳米颗粒是磁热疗的合适候选材料。
