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全球定位系统得出的性能指标是家犬身体活动、疾病及临床治疗效果的反应性指标。

Global positioning system derived performance measures are responsive indicators of physical activity, disease and the success of clinical treatments in domestic dogs.

作者信息

Bruno Elizabeth A, Guthrie James W, Ellwood Stephen A, Mellanby Richard J, Clements Dylan N

机构信息

Royal (Dick) School of Veterinary Studies and The Roslin Institute, The University of Edinburgh, Roslin, Midlothian, United Kingdom.

Wildlife Savvy Ltd, 25 Besselsleigh Road, Wootton, Abingdon, Oxfordshire, United Kingdom.

出版信息

PLoS One. 2015 Feb 18;10(2):e0117094. doi: 10.1371/journal.pone.0117094. eCollection 2015.

Abstract

OBJECTIVE

To assess the use of Global Positioning System receiver (GPS) derived performance measures for differentiating between: 1) different outdoor activities in healthy dogs; 2) healthy dogs and those with osteoarthritis; 3) osteoarthritic dogs before and after treatment with non-steroidal anti-inflammatory analgesia.

DESIGN

Prospective study.

ANIMALS

Ten healthy dogs and seven dogs with osteoarthritis of the elbow joint (OA dogs).

PROCEDURE

Healthy dogs were walked on a standard route on-lead, off-lead and subjected to playing activity (chasing a ball) whilst wearing a GPS collar. Each dog was walked for five consecutive days. Dogs with OA were subjected to a single off-lead walk whilst wearing a GPS collar, and then administered oral Carprofen analgesia daily for two weeks. OA dogs were then subjected to the same walk, again wearing a GPS collar.

RESULTS

GPS derived measures of physical performance could differentiate between on-lead activity, off-lead activity and playing activity in healthy dogs, and between healthy dogs and OA dogs. Variation in the performance measures analysed was greater between individual dogs than for individual dogs on different days. Performance measures could differentiate healthy dogs from OA dogs. OA Dogs treated with Carprofen analgesia showed improvements in their physical performance, which returned to values indistinguishable from those of healthy dogs on nearly all the measures assessed.

CONCLUSIONS AND CLINICAL RELEVANCE

GPS derived measures of physical performance in dogs are objective, easy to quantify, and can be used to gauge the effects of disease and success of clinical treatments. Specific stimuli can be used to modulate physical performance beyond the self-governed boundaries that dogs will naturally express when allowed to exercise freely without stimulation.

摘要

目的

评估利用全球定位系统(GPS)接收器得出的性能指标来区分以下情况:1)健康犬的不同户外活动;2)健康犬与骨关节炎犬;3)骨关节炎犬在接受非甾体抗炎镇痛治疗前后的情况。

设计

前瞻性研究。

动物

10只健康犬和7只肘关节骨关节炎犬(OA犬)。

方法

健康犬佩戴GPS项圈,分别在标准路线上牵绳行走、脱绳行走并进行玩耍活动(追球)。每只犬连续行走5天。OA犬佩戴GPS项圈进行一次脱绳行走,然后每天口服卡洛芬镇痛,持续两周。之后,OA犬再次佩戴GPS项圈进行相同的行走。

结果

GPS得出的身体性能指标能够区分健康犬的牵绳活动、脱绳活动和玩耍活动,也能区分健康犬与OA犬。所分析的性能指标在个体犬之间的差异大于同一犬只在不同日期之间的差异。性能指标能够区分健康犬和OA犬。接受卡洛芬镇痛治疗的OA犬身体性能有所改善,几乎在所有评估指标上都恢复到与健康犬难以区分的值。

结论及临床意义

GPS得出的犬身体性能指标客观、易于量化,可用于评估疾病的影响和临床治疗的效果。特定刺激可用于调节身体性能,使其超出犬只在无刺激自由运动时自然表现的自我控制范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca27/4332864/181659b56bb6/pone.0117094.g001.jpg

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