Chuang Chiung-Cheng, Ye Jing-Jhao, Lin Wan-Chun, Lee Kuan-Ting, Tai Yu-Ting
Department of Biomedical Engineering, Chung Yuan Christian University, Chung Li, 320, Taiwan.
Department of Anaesthesiology, Wan-Fang Hospital, Taipei, Taiwan.
J Clin Monit Comput. 2015 Dec;29(6):801-6. doi: 10.1007/s10877-015-9669-8. Epub 2015 Feb 24.
Heart rate variability (HRV) is a well-known method for the assessment of autonomic nervous function of the heart. Previous study suggested that pulse rate variability (PRV) determined by photoplethysmography could be used instead of HRV to more simply assess autonomic nervous function. However, most research studies included healthy subjects. Thus, the aim of this study was to investigate the feasibility for PRV as a surrogate index for patients with chronic pain. This study investigated the correlation coefficient (by Pearson correlation) and agreement (by Bland-Altman analysis) between PRV and HRV in chronic pain patients in the clinical setting. The results showed high significant correlations (p < 0.001, r > 0.86) between all the HRV and PRV parameters and good agreements (ratio < 0.1) between the parameters in terms of HR, mean RR, VLF, LF, nLF, nHF, and SD1/SD2. Our study suggests that HRV can also be reliably estimated using the photoplethysmography-based PP interval in elderly patients with chronic pain.
心率变异性（HRV）是一种用于评估心脏自主神经功能的知名方法。先前的研究表明，通过光电容积脉搏波描记法测定的脉搏率变异性（PRV）可替代HRV，以更简单地评估自主神经功能。然而，大多数研究纳入的是健康受试者。因此，本研究的目的是探讨PRV作为慢性疼痛患者替代指标的可行性。本研究在临床环境中调查了慢性疼痛患者PRV与HRV之间的相关系数（通过Pearson相关性分析）和一致性（通过Bland-Altman分析）。结果显示，所有HRV和PRV参数之间均存在高度显著相关性（p < 0.001，r > 0.86），并且在心率、平均RR间期、极低频（VLF）、低频（LF）、归一化低频（nLF）、归一化高频（nHF）以及SD1/SD2等参数方面，两者之间具有良好的一致性（比率 < 0.1）。我们的研究表明，在患有慢性疼痛的老年患者中，基于光电容积脉搏波描记法的PP间期也能够可靠地估算HRV。
