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人参和西洋参对动物模型体温调节的影响。

The Effects of Panax ginseng and Panax quinquefolius on Thermoregulation in Animal Models.

作者信息

Hong Bin Na, Do Moon Ho, Her You Ri, Lee Yeong Ro, Kang Tong Ho

机构信息

Department of Audiology, Nambu University, Gwangju 506-824, Republic of Korea ; Department of Oriental Medicinal Materials & Processing, College of Life Sciences, Kyung Hee University, Global Campus, Gyeonggi 446-701, Republic of Korea.

Department of Oriental Medicinal Materials & Processing, College of Life Sciences, Kyung Hee University, Global Campus, Gyeonggi 446-701, Republic of Korea.

出版信息

Evid Based Complement Alternat Med. 2015;2015:748041. doi: 10.1155/2015/748041. Epub 2015 Feb 1.

DOI:10.1155/2015/748041
PMID:25709709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4331477/
Abstract

We devised a study using animal models of hyperthermia and hypothermia and also attempted to accurately assess the effects of Panax ginseng (PG) and Panax quinquefolius (PQ) on body temperature using these models. In addition, we investigated the effects of PG and PQ in our animal models in high and low temperature environments. The results of our experiments show that mice with normothermia, hyperthermia, and hypothermia maintained their body temperatures after a certain period in accordance with the condition of each animal model. In our experiments of body temperature change in models of normal, low, or high room temperature, the hyperthermic model did not show any body temperature change in either the PG- or PQ-administered group. In the normal and low room temperature models, the group administered PG maintained body temperature, while the body temperature of the PQ-administered group was lower than or similar to that of the control group. In conclusion, the fact that PG increases body temperature could not be verified until now. We also showed that the effect of maintaining body temperature in the PG-administered group was superior in a hypothermia-prone low temperature environment.

摘要

我们设计了一项使用体温过高和体温过低动物模型的研究，并尝试利用这些模型准确评估人参（PG）和西洋参（PQ）对体温的影响。此外，我们还研究了PG和PQ在高温和低温环境下对我们动物模型的影响。我们的实验结果表明，体温正常、体温过高和体温过低的小鼠在一段时间后根据每个动物模型的情况维持了它们的体温。在我们关于正常、低温或高温室温模型中体温变化的实验中，高温模型在给予PG或PQ的组中均未显示出任何体温变化。在正常和低温室温模型中，给予PG的组维持了体温，而给予PQ的组体温低于或与对照组相似。总之，PG会升高体温这一事实至今尚未得到证实。我们还表明，在容易发生体温过低的低温环境中，给予PG的组在维持体温方面效果更佳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/5821dc58577e/ECAM2015-748041.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/a19942644a50/ECAM2015-748041.001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/e6f8bdee5885/ECAM2015-748041.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/f08a9a514a3c/ECAM2015-748041.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/8d135c0a4282/ECAM2015-748041.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/b3c0ee7f64b1/ECAM2015-748041.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/5821dc58577e/ECAM2015-748041.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/a19942644a50/ECAM2015-748041.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/4d3da13fd3e5/ECAM2015-748041.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/230c17e276ed/ECAM2015-748041.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/e6f8bdee5885/ECAM2015-748041.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/f08a9a514a3c/ECAM2015-748041.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/8d135c0a4282/ECAM2015-748041.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/b3c0ee7f64b1/ECAM2015-748041.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddb8/4331477/5821dc58577e/ECAM2015-748041.008.jpg

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