Raina Sunil Kumar, Chander Vishav, Raina Sujeet, Kumar Dinesh, Grover Ashoo, Bhardwaj Ashok
Department of Community Medicine, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India.
Department of Medicine, Dr. Rajendra Prasad Government Medical College, Tanda, Kangra, Himachal Pradesh, India.
Ann Indian Acad Neurol. 2015 Jan-Mar;18(1):63-5. doi: 10.4103/0972-2327.151045.
A relation between midlife risk factors (hypertension and diabetes) and dementia has been studied in past and an association has been documented, in spite of some studies pointing to the contrary.
The study was based on post-hoc analysis of data obtained from a study conducted on an elderly population (60 years and above) from selected geographical areas (migrant, urban, rural and tribal) of the Himachal Pradesh state in North-West India.
Analysis of variance revealed an effect of risk factors on cognitive scores; however, post hoc Tukey's honest significant difference (HSD) test revealed that only hypertensives' demonstrated higher chances of scoring lower on cognitive measures.
The possibility that hypertension and diabetes affect dementia needs further evaluation, more so in Indian context.
过去已对中年风险因素（高血压和糖尿病）与痴呆症之间的关系进行了研究，尽管一些研究得出相反结论，但两者之间的关联已有文献记载。
本研究基于对从印度西北部喜马偕尔邦选定地理区域（移民、城市、农村和部落）的老年人群（60岁及以上）进行的一项研究中获取的数据进行的事后分析。
方差分析显示风险因素对认知得分有影响；然而，事后的图基诚实显著差异（HSD）检验表明，只有高血压患者在认知测量中得分较低的可能性更高。
高血压和糖尿病影响痴呆症的可能性需要进一步评估，在印度背景下更是如此。
