Otero Carles, Vilaseca Meritxell, Arjona Montserrat, Martínez-Roda Juan A, Pujol Jaume
J Refract Surg. 2015 Mar;31(3):188-94. doi: 10.3928/1081597X-20150224-03.
To evaluate intersession and intrasession repeatability of aberration data obtained with a new visual simulator based on adaptive optics, which includes a Hartmann-Shack aberrometer (Adaptive Optics Vision Analyzer; Voptica S.L., Murcia, Spain).
Thirty-one healthy right eyes were included in the study. To evaluate intrasession repeatability, three consecutive measurements without repositioning the patient or realigning the eye were obtained. Intersession repeatability was evaluated in three sessions. Aberrometric data computed from the second to the fifth order for a 4-mm pupil were used. Statistical analysis included the repeated measures analysis of variance (or the Wilcoxon signed rank test), the coefficient of repeatability, the Bland-Altman method, and the intraclass correlation coefficient.
No significant differences in the intrasession and intersession repeatability analysis for any of the parameters (P > .05) were found, suggesting a consistent variability of the instrument over time. Similar coefficient of repeatability values were obtained in the three sessions. The Bland-Altman analysis confirmed differences close to zero and the variations were independent of the mean within and between sessions. The intersession intraclass correlation coefficient values were generally above 0.75, suggesting moderate to high repeatability. However, some exceptions were found in the intrasession analysis.
The findings suggest that the new instrument provides consistent and repeatable aberrometric data. It is therefore a suitable tool to perform consistent and repeatable visual simulations.
评估使用基于自适应光学的新型视觉模拟器（包括哈特曼-夏克像差仪，即自适应光学视觉分析仪；西班牙穆尔西亚的Voptica S.L.公司）获取的像差数据在不同测量时段及同一测量时段内的重复性。
31只健康右眼纳入本研究。为评估同一测量时段内的重复性，在不重新安置患者或不对眼睛进行重新校准的情况下进行了连续三次测量。在三个测量时段评估不同测量时段间的重复性。使用针对4毫米瞳孔计算的二阶至五阶像差数据。统计分析包括重复测量方差分析（或威尔科克森符号秩检验）、重复性系数、布兰德-奥特曼方法以及组内相关系数。
在任何参数的同一测量时段内和不同测量时段间的重复性分析中均未发现显著差异（P > 0.05），这表明该仪器随时间具有一致的变异性。在三个测量时段获得了相似的重复性系数值。布兰德-奥特曼分析证实差异接近零，且变异性在测量时段内和测量时段间均与平均值无关。不同测量时段间的组内相关系数值通常高于0.75，表明具有中度至高重复性。然而，在同一测量时段内的分析中发现了一些例外情况。
研究结果表明，该新型仪器可提供一致且可重复的像差数据。因此，它是进行一致且可重复的视觉模拟的合适工具。
