Liu Wenying, Lipner Justin, Moran Christine H, Feng Liangzhu, Li Xiyu, Thomopoulos Stavros, Xia Younan
School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, 30332, USA.
Adv Mater. 2015 Apr 24;27(16):2583-8. doi: 10.1002/adma.201500329. Epub 2015 Mar 10.
Electrospun nanofibers with controllable degrees of crimping are fabricated by simply exposing the samples to a plasticizer at preset shrinkage ratios. Compared with their straight counterparts, the crimped nanofibers are able to mechanically mimic native tendon tissue and better protect tendon fibroblasts under uniaxial strains.
通过简单地将样品以预设的收缩率暴露于增塑剂中,制备出具有可控卷曲度的电纺纳米纤维。与直的纳米纤维相比,卷曲的纳米纤维能够在机械性能上模拟天然肌腱组织,并在单轴应变下更好地保护肌腱成纤维细胞。