Pan Weidong, Wang Mingzhe, Li Mao, Wang Qiudong, Kwak Shin, Jiang Wenfei, Yamamoto Yoshiharu
Department of Neurology, Shuguang Hospital Affiliated to Shanghai University of TCM, 528, Zhangheng Road, Pu-Dong New Area, Shanghai 201203, China.
Department of Neurology, Pudong New Area Hospital of Traditional Chinese Medicine, 460, Xiuchuan Road, Pu-Dong New Area, Shanghai 201200, China.
Evid Based Complement Alternat Med. 2015;2015:343201. doi: 10.1155/2015/343201. Epub 2015 Feb 11.
We evaluated the effects of acupuncture in patients with restless legs syndrome (RLS) by actigraph recordings. Among the 38 patients with RLS enrolled, 31 (M = 12, F = 19; mean age, 47.2 ± 9.7 years old) completed the study. Patients were treated with either standard acupuncture (n = 15) or randomized acupuncture (n = 16) in a single-blind manner for 6 weeks. Changes in nocturnal activity (NA) and early sleep activity (ESA) between week 0 (baseline), week 2, week 4, and week 6 were assessed using leg actigraph recordings, the International Restless Legs Syndrome Rating Scale (IRLSRS), and Epworth Sleepiness Scale (ESS). Standard but not randomized acupuncture reduced the abnormal leg activity of NA and ESA significantly in week 2, week 4, and week 6 based on the changes in the clinical scores for IRLSRS and ESS in week 4 and week 6 compared with the baseline. No side effects were observed. The results indicate that standard acupuncture might improve the abnormal leg activity in RLS patients and thus is a potentially suitable integrative treatment for long-term use.
我们通过活动记录仪评估了针刺疗法对不宁腿综合征（RLS）患者的疗效。在纳入研究的38例RLS患者中，31例（男性12例，女性19例；平均年龄47.2±9.7岁）完成了研究。患者以单盲方式接受标准针刺治疗（n = 15）或随机针刺治疗（n = 16），为期6周。使用腿部活动记录仪、国际不宁腿综合征评分量表（IRLSRS）和爱泼华嗜睡量表（ESS）评估第0周（基线）、第2周、第4周和第6周夜间活动（NA）和早期睡眠活动（ESA）的变化。与基线相比，基于第4周和第6周IRLSRS和ESS临床评分的变化，标准针刺而非随机针刺在第2周、第4周和第6周显著降低了NA和ESA的异常腿部活动。未观察到副作用。结果表明，标准针刺可能改善RLS患者的异常腿部活动，因此是一种潜在适合长期使用的综合治疗方法。
