Boulangé Alain, Lejon Veerle, Berthier David, Thévenon Sophie, Gimonneau Geoffrey, Desquesnes Marc, Abah Samuel, Agboho Prudenciène, Chilongo Kalinga, Gebre Tsegaye, Fall Assane Gueye, Kaba Dramane, Magez Stefan, Masiga Daniel, Matovu Enock, Moukhtar Aldjibert, Neves Luis, Olet Pamela A, Pagabeleguem Soumaïla, Shereni William, Sorli Brice, Taioe Moeti O, Tejedor Junco María Teresa, Yagi Rehab, Solano Philippe, Cecchi Giuliano
CIRAD, UMR INTERTRYP, Bouaké, 01 BP 1500, Cote d'Ivoire.
CIRAD, IRD, INTERTRYP, Univ of Montpellier, Montpellier, F-34398, France.
Open Res Eur. 2022 Aug 15;2:67. doi: 10.12688/openreseurope.14759.2. eCollection 2022.
Vector-borne diseases affecting livestock have serious impacts in Africa. Trypanosomosis is caused by parasites transmitted by tsetse flies and other blood-sucking . The animal form of the disease is a scourge for African livestock keepers, is already present in Latin America and Asia, and has the potential to spread further. A human form of the disease also exists, known as human African trypanosomosis or sleeping sickness. Controlling and progressively minimizing the burden of animal trypanosomosis (COMBAT) is a four-year research and innovation project funded by the European Commission, whose ultimate goal is to reduce the burden of animal trypanosomosis (AT) in Africa. The project builds on the progressive control pathway (PCP), a risk-based, step-wise approach to disease reduction or elimination. COMBAT will strengthen AT control and prevention by improving basic knowledge of AT, developing innovative control tools, reinforcing surveillance, rationalizing control strategies, building capacity, and raising awareness. Knowledge gaps on disease epidemiology, vector ecology and competence, and biological aspects of trypanotolerant livestock will be addressed. Environmentally friendly vector control technologies and more effective and adapted diagnostic tools will be developed. Surveillance will be enhanced by developing information systems, strengthening reporting, and mapping and modelling disease risk in Africa and beyond. The socio-economic burden of AT will be assessed at a range of geographical scales. Guidelines for the PCP and harmonized national control strategies and roadmaps will be developed. Gender equality and ethics will be pivotal in all project activities. The COMBAT project benefits from the expertise of African and European research institutions, national veterinary authorities, and international organizations. The project consortium comprises 21 participants, including a geographically balanced representation from 13 African countries, and it will engage a larger number of AT-affected countries through regional initiatives.
影响家畜的媒介传播疾病在非洲造成了严重影响。锥虫病由采采蝇和其他吸血昆虫传播的寄生虫引起。该疾病的动物形式对非洲家畜饲养者来说是一场灾难，已在拉丁美洲和亚洲出现，并有可能进一步传播。该疾病也存在人类形式，即人类非洲锥虫病或昏睡病。控制并逐步减轻动物锥虫病负担（COMBAT）是一个由欧盟委员会资助的为期四年的研究与创新项目，其最终目标是减轻非洲动物锥虫病（AT）的负担。该项目建立在渐进式控制途径（PCP）基础之上，这是一种基于风险、逐步减少或消除疾病的方法。COMBAT将通过提高对动物锥虫病的基础知识、开发创新控制工具、加强监测、使控制策略合理化、建设能力和提高认识来加强动物锥虫病的控制和预防。将解决疾病流行病学、媒介生态学和能力以及耐锥虫家畜生物学方面的知识空白。将开发环境友好型媒介控制技术以及更有效和适用的诊断工具。将通过开发信息系统、加强报告以及绘制和模拟非洲及其他地区的疾病风险来加强监测。将在一系列地理尺度上评估动物锥虫病的社会经济负担。将制定渐进式控制途径指南以及统一的国家控制策略和路线图。性别平等和道德将在所有项目活动中发挥关键作用。COMBAT项目受益于非洲和欧洲研究机构、国家兽医当局和国际组织的专业知识。该项目联盟由21个参与者组成，包括来自13个非洲国家的地域均衡代表，并将通过区域倡议让更多受动物锥虫病影响的国家参与进来。
