Autonomic Unit and Hypertension Unit, Department of Medical Sciences, University of Torino, Torino, Italy,
Clin Auton Res. 2015 Jun;25(3):133-40. doi: 10.1007/s10286-015-0275-0. Epub 2015 Mar 20.
Patients with autonomic failure are characterized by orthostatic hypotension, supine hypertension, high blood pressure variability, blunted heart rate variability, and often have a "non-dipping" or "reverse dipping" pattern on 24-h ambulatory blood pressure monitoring. These alterations may lead to cardiovascular and cerebrovascular changes, similar to the target organ damage found in hypertension. Often patients with autonomic failure are on treatment with anti-hypotensive drugs, which may worsen supine hypertension. The aim of this review is to summarize the evidence for cardiac, vascular, renal, and cerebrovascular damage in patients with autonomic failure.
自主神经衰竭患者的特征是直立性低血压、仰卧位高血压、血压变异性高、心率变异性减弱，并且在 24 小时动态血压监测中常常呈现“非杓型”或“反杓型”模式。这些改变可能导致心血管和脑血管变化，类似于高血压中发现的靶器官损伤。自主神经衰竭患者通常接受抗低血压药物治疗，这可能会加重仰卧位高血压。本综述的目的是总结自主神经衰竭患者心脏、血管、肾脏和脑血管损伤的证据。
