Acupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi'er Qiao Road, Chengdu, Sichuan 610075, China.
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, 10117 Berlin, Germany.
Evid Based Complement Alternat Med. 2015;2015:380615. doi: 10.1155/2015/380615. Epub 2015 Feb 22.
Chronic fatigue syndrome (CFS) is a debilitating and complex disorder characterized by profound fatigue with uncertain pathologic mechanism. Neuroimage may be an important key to unveil the central nervous system (CNS) mechanism in CFS. Although most of the studies found gray matter (GM) volumes reduced in some brain regions in CFS, there are many factors that could affect GM volumes in CFS, including chronic pain, stress, psychiatric disorder, physical activity, and insomnia, which may bias the results. In this paper, through reviewing recent literatures, we discussed these interferential factors, which overlap with the symptoms of CFS.
慢性疲劳综合征（CFS）是一种使人虚弱和复杂的疾病，其特征是疲劳严重且发病机制不确定。神经影像学可能是揭示慢性疲劳综合征中枢神经系统（CNS）机制的重要关键。尽管大多数研究发现慢性疲劳综合征患者大脑某些区域的灰质（GM）体积减少，但有许多因素会影响慢性疲劳综合征患者的 GM 体积，包括慢性疼痛、压力、精神障碍、身体活动和失眠，这些因素可能会影响研究结果。在本文中，我们通过回顾最近的文献，讨论了这些与慢性疲劳综合征症状重叠的干扰因素。
