Santoro Amato, Alvino Federico, Antonelli Giovanni, Cassano Francesco Emmanuel, De Vito Raffaella, Cameli Matteo, Mondillo Sergio
University of Siena, Siena, Tuscany, Italy,
Int J Cardiovasc Imaging. 2015 Mar;31(3):567-73. doi: 10.1007/s10554-015-0592-3. Epub 2015 Jan 21.
Diastolic function get worse with increasing age. Aim of this study was to investigate the impact of aerobic training on diastolic function with increasing age with speckle tracking echocardiography. We enrolled 125 amateur swimmers (AG), divided in three groups at increasing age: young athletes, adult athletes (AG2), old athletes (AG3). We enrolled 95 sedentary controls (SG) age-matched with athletes and divided into three groups: young sedentary group, adult sedentary group (SG2) and old sedentary group (SG3). AG had better diastolic function than SG. AG showed lower left ventricular twist than controls. E/A ratio got worse at increasing of age in all population (r = -0.34; p < 0.001); particularly in SG2 and SG3 there was a worsening of diastolic function respect to diastolic function of AG2 and AG3; in fact E/A ratio decreased with aging. Furthermore in SG E/A ratio showed a linear correlation with age (r = -0.54; p < 0.001); in AG this correlation was lost. Therefore the training and age were independent predictor of E/A (respectively β = -0.27; p = 0.004; β = -0.24, p = 0.008). Regular and aerobic training may minimize aging changes of diastolic function. This training-effect may play a key role to preserve diastolic filling in older athletes.
舒张功能会随着年龄的增长而变差。本研究的目的是通过斑点追踪超声心动图研究有氧训练对随着年龄增长的舒张功能的影响。我们招募了125名业余游泳运动员（AG组），按照年龄增长分为三组：年轻运动员组、成年运动员组（AG2组）、老年运动员组（AG3组）。我们招募了95名与运动员年龄匹配的久坐不动的对照组（SG组），并将其分为三组：年轻久坐组、成年久坐组（SG2组）和老年久坐组（SG3组）。AG组的舒张功能优于SG组。AG组的左心室扭转低于对照组。在所有人群中，随着年龄增长E/A比值变差（r = -0.34；p < 0.001）；特别是在SG2组和SG3组中，相对于AG2组和AG3组的舒张功能，舒张功能出现恶化；事实上，E/A比值随着年龄增长而降低。此外，在SG组中，E/A比值与年龄呈线性相关（r = -0.54；p < 0.001）；在AG组中这种相关性消失。因此，训练和年龄是E/A的独立预测因素（分别为β = -0.27；p = 0.004；β = -0.24，p = 0.008）。规律的有氧训练可能会使舒张功能的衰老变化最小化。这种训练效果可能在维持老年运动员的舒张期充盈方面起关键作用。
