Yochim Brian P, Beaudreau Sherry A, Kaci Fairchild J, Yutsis Maya V, Raymond Neda, Friedman Leah, Yesavage Jerome
1VA Palo Alto Health Care System,Palo Alto,California.
J Int Neuropsychol Soc. 2015 Mar;21(3):239-48. doi: 10.1017/S1355617715000120. Epub 2015 Mar 24.
Naming or word-finding tasks are a mainstay of the typical neuropsychological evaluation, particularly with older adults. However, many older adults have significant visual impairment and there are currently no such word-finding tasks developed for use with older visually impaired populations. This study presents a verbal, non-visual measure of word-finding for use in the evaluation of older adults with possible dysnomia. Stimuli were chosen based on their frequency of usage in everyday spoken language. A 60-item scale was created and given to 131 older Veterans. Rasch analyses were conducted and differential item functioning assessed to eliminate poorly-performing items. The final 55-item scale had a coefficient alpha of 0.84 and correlated with the Neuropsychological Assessment Battery Naming test, r=0.84, p<.01, Delis-Kaplan Executive Function System (D-KEFS) Category Fluency, r=0.45, p<.01, and the D-KEFS Letter Fluency, r=0.40, p<.01. ROC analyses found the measure to have sensitivity of 79% and specificity of 85% for detecting dysnomia. Patients with dysnomia performed worse on the measure than patients with intact word-finding, t(84)=8.2, p<.001. Patients with no cognitive impairment performed significantly better than patients with mild cognitive impairment, who performed significantly better than patients with dementia. This new measure shows promise in the neuropsychological evaluation of word-finding ability in older adults with or without visual impairment. Future directions include the development of a shorter version and the generation of additional normative data.
命名或找词任务是典型神经心理学评估的主要内容,在老年人中尤为如此。然而,许多老年人有严重的视力障碍,目前还没有专门为视力受损的老年人群体开发的找词任务。本研究提出了一种用于评估可能存在命名障碍的老年人的言语性、非视觉性找词测量方法。根据日常口语中的使用频率选择刺激词。创建了一个包含60个条目的量表,并将其施测于131名老年退伍军人。进行了拉施分析并评估了项目功能差异,以剔除表现不佳的项目。最终的55个条目量表的α系数为0.84,与神经心理评估量表命名测试的相关性为r = 0.84,p <.01,与德利斯-卡普兰执行功能系统(D-KEFS)类别流畅性的相关性为r = 0.45,p <.01,与D-KEFS字母流畅性的相关性为r = 0.40,p <.01。ROC分析发现该测量方法检测命名障碍的敏感性为79%,特异性为85%。命名障碍患者在该测量方法上的表现比找词能力正常的患者差,t(84)=8.2,p <.001。无认知障碍的患者表现明显优于轻度认知障碍患者,轻度认知障碍患者表现明显优于痴呆患者。这种新的测量方法在评估有或无视力障碍的老年人找词能力的神经心理学评估中显示出前景。未来的方向包括开发一个更简短的版本以及生成更多的常模数据。