Badwan Adnan A, Rashid Iyad, Omari Mahmoud M H Al, Darras Fouad H
Research and Innovation Center (RIC), The Jordanian Pharmaceutical Manufacturing Co., P.O. Box 94, Naor 11710, Jordan.
Mar Drugs. 2015 Mar 19;13(3):1519-47. doi: 10.3390/md13031519.
Despite the numerous uses of chitin and chitosan as new functional materials of high potential in various fields, they are still behind several directly compressible excipients already dominating pharmaceutical applications. There are, however, new attempts to exploit chitin and chitosan in co-processing techniques that provide a product with potential to act as a direct compression (DC) excipient. This review outlines the compression properties of chitin and chitosan in the context of DC pharmaceutical applications.
尽管几丁质和壳聚糖作为具有高潜力的新型功能材料在各个领域有众多用途，但它们仍落后于一些已在制药应用中占主导地位的直接压片辅料。然而，目前有新的尝试在共处理技术中利用几丁质和壳聚糖，以提供一种有可能用作直接压片（DC）辅料的产品。本综述概述了几丁质和壳聚糖在DC制药应用背景下的压缩特性。
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