Department of Public Health, Yonsei University Graduate School, Seoul, Korea.
Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea.
Korean Circ J. 2015 Mar;45(2):141-8. doi: 10.4070/kcj.2015.45.2.141. Epub 2015 Mar 24.
To investigate age-specific and sex-specific distributions of blood cholesterol in the general Korean population.
We analyzed data for 8284 men and 9246 women aged ≥10 years who participated in the fifth (2010-2012) Korea National Health and Nutrition Examination Survey. Age-specific means, medians, and selected percentiles were calculated for men, premenopausal women, and postmenopausal women.
Median total cholesterol (TC) level increased with age across all age groups, from 147 to 196 mg/dL in males and from 159 to 210 mg/dL in females. Triglyceride (TG) levels increased with age in females; however, in males, TG levels rapidly increased during young adulthood, peaked at 50-54 years, and then decreased. High density lipoprotein-cholesterol (HDL-C) levels were higher in females than in males and decreased with increasing age in both males and females. Low density lipoprotein-cholesterol (LDL-C) levels increased with age across all age groups, from 89 to 127 mg/dL in males and from 82 to 113 mg/dL in females. Lipoprotein-cholesterol fraction (TC/HDL-C, LDL-C/HDL-C, TG/HDL-C, non-HDL-C) levels increased with age in females, but increased more rapidly in males during young adulthood and decreased after middle age.
Blood cholesterol levels and lipoprotein-cholesterol fractions present different distributions by age, sex, and menopausal status.
调查韩国普通人群中特定年龄段和性别人群的血液胆固醇分布情况。
我们分析了参加 2010-2012 年第五次韩国国家健康和营养调查的 8284 名男性和 9246 名年龄≥10 岁的女性的数据。计算了男性、绝经前女性和绝经后女性各年龄段的总胆固醇（TC）均值、中位数和特定百分位数。
TC 水平在所有年龄段的男性中均随年龄增长而升高，从 147 升至 196mg/dL；在女性中则从 159 升至 210mg/dL。女性的甘油三酯（TG）水平随年龄增长而升高；而男性的 TG 水平在青年期迅速升高，在 50-54 岁达到峰值，然后下降。女性的高密度脂蛋白胆固醇（HDL-C）水平高于男性，且在男性和女性中均随年龄增长而降低。低密度脂蛋白胆固醇（LDL-C）水平在所有年龄段的男性和女性中均随年龄增长而升高，从 89 升至 127mg/dL，从 82 升至 113mg/dL。女性的脂蛋白胆固醇（TC/HDL-C、LDL-C/HDL-C、TG/HDL-C、非 HDL-C）水平随年龄增长而升高，但在青年期男性的增长更为迅速，中年后则下降。
血液胆固醇水平和脂蛋白胆固醇分数的分布因年龄、性别和绝经状态而异。
