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一名克罗恩病患者的肺上皮样血管内皮瘤

Pulmonary epithelioid hemangioendothelioma in a patient with Crohn's disease.

作者信息

Ramchandar Nanda, Wojtczak Henry A

机构信息

Naval Medical Center San Diego, Department of Pediatrics, 34800 Bob Wilson Drive, San Diego, CA 92134, USA.

出版信息

Case Rep Pediatr. 2015;2015:491960. doi: 10.1155/2015/491960. Epub 2015 Feb 28.

DOI:10.1155/2015/491960
PMID:25815232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4359810/
Abstract

Pulmonary epithelioid hemangioendothelioma (PEH) is a rare neoplasm, largely unresponsive to chemotherapeutic medications, and with varied prognosis. Imaging on computerized tomography may demonstrate perivascular nodules, but diagnosis is ultimately made on biopsy with immunohistochemical analysis. Here we describe a case of PEH in a 14-year-old male with Crohn's disease, which, to our knowledge, has not previously been described in the literature.

摘要

肺上皮样血管内皮瘤(PEH)是一种罕见的肿瘤,对化疗药物大多无反应,预后各异。计算机断层扫描成像可能显示血管周围结节,但最终诊断需通过活检及免疫组化分析来确定。在此,我们描述一例14岁患有克罗恩病的男性肺上皮样血管内皮瘤病例,据我们所知,此前文献中尚未有过相关描述。

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本文引用的文献

1
CAMTA1 immunostaining is not useful in differentiating epithelioid hemangioendothelioma from its potential mimickers.CAMTA1免疫染色对于鉴别上皮样血管内皮瘤与其潜在的模仿者并无帮助。
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N Engl J Med. 2014 Dec 18;371(25):2418-27. doi: 10.1056/NEJMcpc1410938.
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Clinicopathological characteristics of pulmonary epithelioid hemangioendothelioma: A report of four cases and review of the literature.
肺上皮样血管内皮瘤的临床病理特征:4例报告并文献复习
Oncol Lett. 2014 Dec;8(6):2517-2522. doi: 10.3892/ol.2014.2566. Epub 2014 Sep 26.
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Thoracic epithelioid malignant vascular tumors: a clinicopathologic study of 52 cases with emphasis on pathologic grading and molecular studies of WWTR1-CAMTA1 fusions.胸内上皮样恶性血管肿瘤:52 例临床病理研究,重点是病理分级和 WWTR1-CAMTA1 融合的分子研究。
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Lung Cancer. 2014 Mar;83(3):411-5. doi: 10.1016/j.lungcan.2013.12.015. Epub 2014 Jan 7.
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Pulmonary epithelioid hemangioendothelioma.肺上皮样血管内皮瘤
Isr Med Assoc J. 2011 Nov;13(11):676-9.
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Pleural epithelioid hemangioendothelioma in an elderly patient. A case report and review of the literature.老年患者的胸膜上皮样血管内皮细胞瘤。病例报告及文献复习。
Lung Cancer. 2011 Jul;73(1):116-9. doi: 10.1016/j.lungcan.2011.04.003. Epub 2011 May 17.
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Pulmonary epithelioid hemangioendothelioma.肺上皮样血管内皮瘤
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10
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Therap Adv Gastroenterol. 2010 May;3(3):203-6. doi: 10.1177/1756283X10363015.